Branscum et al., "Sclerostin and Dickkopf-1 in renal osteodystrophy
," Clinical Journal of the American Society of Nephrology, vol.
(2) Renal osteodystrophy
, as in the patient presented here, is the term used to describe the combination of renal dysfunction coupled with hyperparathyroidism and the associated soft tissue and skeletal changes.
Causes of pain in patients (n = 53) Cause of pain n (a) % Surgical trauma 23 43.3 Peripheral vascular disease 17 32.1 Osteoarthritis 5 9.4 Inflammatory arthritis 5 9.4 Renal osteodystrophy
4 7.5 Osteomyelitis 1 1.9 Osteoporosis 1 1.9 Pain related to dialysis procedure 14 26.4 Peripheral neuropathy 10 18.9 Malignancy 5 9.4 Gout 3 5.7 Calciphylaxis 2 3.8 Polycystic kidney disease 1 1.9 (a) Numbers add up to more than 53 (100%) because 28 patients (53%) had more than 1 cause of pain.
. Normal bone growth is regulated by the interaction of parathyroid hormone (PTH), calcium, phosphorus, and vitamin D.
in the setting of hyperparathyroidism, leontiasis ossea pattern.
It additionally includes renal osteodystrophy
, which develops in the majority of CKD patients.
Definitions of CKD-MBD, Renal Osteodystrophy
, and Osteoporosis
Calcimimetics: Anew tool for management of hyerparathyroidism and renal osteodystrophy
in patients with chronic kidney disease.
Reduction of PTH has been shown to result in an improvement in renal osteodystrophy
. When administered by bolus injection, Calcitriol is rapidly available in the blood stream.
We present herein a case of non-traumatic spontaneous simultaneous bilateral femoral neck fracture in a 32 year old male patient, secondary to renal osteodystrophy
. Our aim is to present a rare case that we came across.
The etiology of pain may be secondary to co-morbidities (e.g., diabetes, vascular disease), the primary renal disease (e.g., polycystic kidney disease), consequences of renal failure (e.g., calciphylaxis, renal osteodystrophy
), or the dialysis treatment itself (e.g., recurrent needle insertion, arteriovenous fistulas).