renal osteodystrophy

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osteodystrophy

[os″te-o-dis´trŏ-fe]

abnormal development of bone.

renal osteodystrophy a condition due to chronic kidney disease and renal failure, marked by impaired vitamin D metabolism, elevated serum phosphorus levels, low or normal serum calcium levels, and stimulation of parathyroid function. There may be any of various bone diseases, including osteitis fibrosa cystica, osteomalacia, osteoporosis, and sometimes osteosclerosis. If onset is in childhood, renal dwarfism may result.

re·nal os·te·o·dys·tro·phy

generalized bone changes resembling osteomalacia and rickets or osteitis fibrosa, occurring in children or adults with chronic renal failure.

renal osteodystrophy

a condition resulting from chronic renal failure and characterized by uneven bone growth and demineralization. See also renal nanism, renal rickets.

re·nal os·te·o·dys·tro·phy

(rē'năl os'tē-ō-dis'trŏ-fē)

Generalized bone changes resembling osteomalacia and rickets or osteitis fibrosa, occurring in chronic renal failure.

osteodystrophy

diseases of bone in which there is failure of normal development or abnormal metabolism in bone which is already mature. Principal clinical signs are distortion and enlargement of bones, susceptibility to fracture, and abnormalities of gait and posture. See also osteodystrophia fibrosa.

hypertrophic osteodystrophy

a disease of unknown etiology that occurs in young, rapidly growing dogs primarily of the large or giant breeds, in which there is pain and soft tissue swelling usually around the distal radius, ulna and tibia, lameness, and varying degrees of fever, lethargy and anorexia. Periosteal new bone is formed around the metaphyses and sometimes diaphyses, contributing to the enlargement of the limbs. The cause is unknown but hypovitaminosis C has at various times been suggested. Called also Möller-Barlow's disease (from a similar human disease), Barlow's disease, skeletal scurvy, infantile scurvy, osteodystrophy II, metaphyseal osteopathy, canine hypertrophic osteodystrophy.

renal osteodystrophy

see renal secondary hyperparathyroidism.

Hypertrophic osteodystrophy in a 4-month-old Great Dane. By permission from Lamb CR, Diagnostic Imaging of the Dog and Cat, Mosby, 1993

References in periodicals archive ?

Unique imaging findings in the facial bones of renal osteodystrophy.

Leontiasis ossea

Diagnosis, assessment, and treatment of bone turnover abnormalities in renal osteodystrophy.

The evaluation of renal osteodystrophy in patients on hemodialysis by biochemical and radiological methods/Hemodiyaliz hastalarinda renal osteodistrofinin radyolojik ve biyokimyasal yontemlerle degerlendirilmesi

Optimal management of renal osteodystrophy includes timing the phosphate binders to coincide with meal times and

Management of pediatric patients with chronic kidney disease

Renal Osteodystrophy is usually a diagnosis of end stage renal disease.

Spontaneous simultaneous bilateral femoral neck fracture secondary to renal osteodystrophy: a case report & review of literature

Calcium/phosphorus imbalances, aluminum toxicity, and renal osteodystrophy.

End stage renal disease in children: diagnosis, management, and interventions

The combination of secondary hyperparathyroidism and mineralization defects (osteomalacia) represents the most common form of renal osteodystrophy (ROD).

A case of renal osteodystrophy with unexpected serum intact parathyroid hormone concentrations

For brevity, this article will focus on how the management of anemia and renal osteodystrophy has evolved, and how immunosuppressive drugs transformed the field of transplantation.

A brief history in nephrology pharmacotherapy

Alterations in mineral and bone metabolism among patients with chronic kidney disease (CKD) have historically been termed renal osteodystrophy because of the characteristic bone changes that are apparent on biopsy.

Consequences of chronic kidney disease--mineral and bone disorder: a progressive disease

Calcimimetics are still being studied in humans to see if the observed rapid suppression of PTH leads to an improvement in signs of renal osteodystrophy.

Calcimimetic agents for the treatment of secondary hyperparathyroidism

Renal osteodystrophy is one of the major complications in hemodialysis (HD) [3] patients, leading to a substantial increase in fracture rate and increased morbidity and mortality (1).

Serum concentrations of cross-linked N-telopeptides of type I collagen: new marker for bone resorption in hemodialysis patients