angiomyolipoma

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angiomyolipoma

 [an″je-o-mi″o-lĭ-po´mah]
a benign tumor containing vascular, adipose, and muscle elements, occurring most often in the kidney with smooth muscle elements.

an·gi·o·my·o·li·po·ma

(an'jē-ō-mī'ō-li-pō'mă),
A benign neoplasm of adipose tissue (lipoma) in which muscle cells and vascular structures are fairly conspicuous; most commonly a renal tumor containing smooth muscle, often associated with tuberous sclerosis.
[angio- + G. mys, muscle, + lipos, fat, + -oma, tumor]

angiomyolipoma

(ăn′jē-ō-mī′ō-lĭ-pō′mə)
n.
A benign tumor composed of adipose tissue, muscle cells, and vascular structures.

angiomyolipoma

A benign, well-circumscribed, nonencapsulated tumour-like lesion or hamartoma (perivascular epithelioid cell tumour—PEComa), which is the most common mesenchymal lesion of the kidney. It is composed of blood vessels, smooth muscle and mature fat, and is typically seen in the kidney or paranephric tissue. Angiomyolipoma also occurs in the fallopian tube, liver, nasal cavity, penis, skin, spermatic cord and vagina, and can mimic renal cell carcinoma. Up to 50% of patients have tuberous sclerosis (TS); 75% of TS patients have angiomyolipomas.

Clinical findings
May cause catastrophic bleeds.
 
Molecular pathology
TSC1 and TSC2 mutations.

an·gi·o·my·o·li·po·ma

(an'jē-ō-mī'ō-li-pō'mă)
A benign neoplasm of adipose tissue (lipoma) in which muscle cells and vascular structures are fairly conspicuous.
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References in periodicals archive ?
A case of renal angiomyolipoma was observed in our study.
Spontaneous Retroperitoneal Hemorrhage (Wunderlich Syndrome) due to Large Upper Pole Renal Angiomyolipoma: Does Robotic-Assisted Laparoscopic Partial Nephrectomy Have a Role in Primary Treatment?
The biopsies that were performed were diagnostic (100%, 6/6) and showed renal angiomyolipoma in patient 1, adrenal adenoma in patient 2, renal cell carcinoma in patient 3, solitary fibrous tumor in patient 13, and renal cell carcinoma in patient 14.
In these, the majority of USS (32/35) were reported as normal, while two patients had reports which commented on dilated renal collecting systems (on the subsequent CTU scans one result was reported as normal while the other confirmed benign extrarenal pelvis), and one (1.8%) patient had a 1.6 cm renal angiomyolipoma (AML).
Renal angiomyolipoma (AML) is a benign hamartomatous tumor comprising variable amounts of adipose tissue, smooth muscle, and abnormal blood vessels.
Afinitor is the only approved non-surgical option indicated for treating TSC-associated non-cancerous brain tumors (subependymal giant cell astrocytoma, or SEGA) and TSC-associated kidney tumors (renal angiomyolipoma).
Casimiro, "Wunderlich's syndrome, or spontaneous retroperitoneal hemorrhage, in a patient with tuberous sclerosis and bilateral renal angiomyolipoma," American Journal of Case Reports, vol.
Occult renal cell carcinoma of eosinophilic morphology detected within renal angiomyolipoma mass in a patient with tuberous sclerosis complex.
However, a diagnosis of TSC was not made, even in presence of these classical clinical features, leading to patient presenting now at 32-year of age with known renal complications of bilateral renal angiomyolipoma, which was causing obstruction and pain as they enlarged.
Prevalence of sporadic renal angiomyolipoma: a retrospective analysis of 61,389 in- and out-patients.