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System consolidation is the process of time-dependent gradual reorganization of the brain regions supporting remote memory storage.
We cannot exclude that these effects of EE might have contributed to our results, for instance, via a better encoding/local consolidation process in the hippocampus, especially in the case of the better performance of EE animals at the 24 h interval, where early tagging in PFC is not supposed to play a key role; enhanced synaptic function and plasticity in EE animals might also have contributed to our results enhancing the efficacy of the hippocampal-cortical dialogue during formation of the cortical trace which supports remote memory.
Our work uses hardware support for directly accessing remote memory, which is available in several modern parallel architectures and workstation clusters [Ibel et al.
Correlation coefficients (Pearson) between CAMCOG sub-scores and total CAMCOG scores Alzheimer's Vascular disease dementia SDLT(*) Orientation 0.69 0.84 0.57 Comprehension 0.74 0.87 0.87 Expression 0.77 0.82 0.76 Praxis 0.68 0.75 0.87 Recent memory 0.58 0.73 0.36 Visual memory 0.55 0.74 0.67 Remote memory 0.69 2.92 0.60 Attention and calculation 0.49 0.82 0.68 Perception 0.61 0.77 0.79 Abstract thinking 0.55 0.62 0.09 Verbal fluency 0.56 0.73 0.54 (*) Senile dementia of Lewy body type.
The aCC was found to be activated after remote memory recall in a number of tasks [47, 48, 54, 55], and, conversely, inactivation of the aCC disrupted recall of remote five-arm discrimination [47], contextual fear [48], and MWM [55] memories.
Remote memory takes longer to access because the memory request is routed in hardware from the requesting processor to whichever remote processor has that particular datum in local memory.
The average times to fetch a 4KB block in the local cache, the cache of another client and the server are shown in the rows Local Memory Latency, Remote Memory Latency, and Server Access Latency.
IBM says the technique won't be used to replace existing DRAM memory, however, and as much of the current debate about computer system design revolves around the time penalty (and software problems) associated with accessing remote memory sources, the technique is significant, it claims.
Memory allocation algorithms that are not aware of the large difference in local versus remote memory access latencies on NUMA (Non-Uniform Memory Access time) systems lead to suboptimal application performance.
Sequent says that as memory latencies - the time penalty for having to fetch instructions from remote memory rather than local memory - are halving each year, the whole latency issue is going to fade away quickly.
The new servers offer support for up to 64Gb of main memory and 48Tb of connected storage and include a fibre channel subsystem and dynamic partitioning capabilities as well as enhanced system throughput and reduced local and remote memory access times.

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