releasing hormone


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re·leas·ing fac·tors (RF),

1. any substance, usually of hypothalamic origin, capable of accelerating the rate of secretion of a given hormone by the anterior pituitary gland;
2. factors required in the termination phase of either RNA biosynthesis or protein biosynthesis. Synonym(s): termination factor
3. colloquial shortened form for the HMG-CoA reductase inhibitors used as antihyperlipidemic agents, whose generic names end with the suffix statin. Synonym(s): statins

re·leas·ing fac·tors

(rĕ-lēs'ing fak'tŏrz)
1. Substances, usually of hypothalamic origin, capable of accelerating the rate of secretion of a given hormone by the anterior pituitary gland.
2. Factors required in the termination phase of either RNA biosynthesis or protein biosynthesis.
Synonym(s): liberins, releasing hormone.

releasing hormone

Abbreviation: RH
Any of a group of substances secreted by the hypothalamus that control or inhibit the release of various hormones. They include thyrotropin-releasing hormone, gonadotropin-releasing hormone, dopamine, growth hormone-releasing hormone, corticotropin-releasing hormone, and somatostatin. Dopamine and somatostatin act to inhibit release of the hormones they act upon.
See also: hormone
References in periodicals archive ?
Differential effects of gonadotropin releasing hormone (GnRH)-I and GnRH-II on prostate cancer cell signaling and death.
IGHD type 1b is caused by mutations in either the GH-1 gene or the growth hormone releasing hormone receptor gene.
Expression of gonadotrophin releasing hormone receptor I is a favorable prognostic factor in epithelial ovarian cancer.
Corticotropin releasing hormone. A diagnostic marker for behavioral and reproductive disorders?
It is already known that stress boosts levels of stress hormones - glucocorticoids such as cortisol - that inhibit the body's main sex hormone, gonadotropin releasing hormone (GnRH), and subsequently suppresses sperm count, ovulation and sexual activity.
With the potential for large quantities of patches releasing hormone into the environment, he says, "you have to, in fact, be concerned."
During aging there are several changes which contribute to the decline in GH/IGF-I including changes in signal to the somatotrophs from growth hormone releasing hormone, somatostatin and other factors such as body composition, exercise, diet and sleep.
While investigating some of these synthetic drugs that stimulate the release of growth hormone, researchers discovered that several don't work through the brain's well-known triggering agent, which is called growth hormone releasing hormone. Instead, scientists learned that the drugs act upon a previously unrecognized cell-surface protein, or receptor, in the brain's pituitary and hypothalamus.
The product is the only LHRH (luteinising hormone releasing hormone) agonist with the innovative, controlled-release ATRIGEL Delivery System.
According to the company, ELIGARD is the only LHRH (luteinizing hormone releasing hormone) agonist with the innovative, controlled-release ATRIGEL[R] Delivery System.
Other researchers are replacing the progestins in such experiments with drugs that block the action of a hormone known as gonadotropin releasing hormone, or GnRH.
The company is studying the efficacy and safety of the gonadotropin releasing hormone agonist, analogue triptorelin pamoate six-month formulation, in the treatment of children suffering from central (GnRH-dependent) precocious puberty.