relaxin


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.

re·lax·in

(rē-lak'sin),
A polypeptide hormone secreted by the corpora lutea of mammalian species during pregnancy. Facilitates the birth process by causing a softening and lengthening of the pubic symphysis and cervix; it also inhibits contraction of the uterus and may play a role in timing of parturition.
[relax + -in]

relaxin

(rĭ-lăk′sĭn)
n.
A female hormone secreted by the corpus luteum that helps soften the cervix and relax the pelvic ligaments in childbirth.

re·lax·in

(rĕ-lak'sin)
Polypeptide hormone secreted by the corpora lutea of mammalian species during pregnancy; facilitates birth process by softening and lengthening the pubic symphysis and cervix.

relaxin

A polypeptide found in the corpus luteum of various mammals that softens the neck of the womb (cervix) and relaxes the pubic joint of the pelvis to ease childbirth. Relaxin has not been proved to occur in humans.
References in periodicals archive ?
In conclusion, our study shows that H2 relaxin can inhibit ioversol induced apoptosis, possibly via activation of the PI3K/Akt signaling pathway.
Ripening of the human cervix and induction of labor with intracervical purified porcine relaxin. Obstet Gynecol.
Davison et al., "Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes," Journal of the American College of Cardiology, vol.
Weight training - You will still have a hormone called relaxin flowing around your body, which makes the joints softer and more supple.
'Relaxin for the treatment of patients with acute heart failure (RELAX-AHF)' calismasinda akut kalp yetersizligi hastalarinda relaksinin etkileri arastirilmis ve relaksin ile dispnenin erkenden duzeldigi ve 60 gunluk takip suresinde kardiyovaskuler olum ve hastaneye tekrar yatis ve renal disfonksiyon oranlarinda anlamli azalma oldugu saptanmistir (45).
The menstrual cycle is controlled by the pituitary-hypothalamic-ovarian axis and involves the complex interaction of estrogen, progesterone, relaxin and testosterone.
Felker et al., "Relaxin for the treatment of patients with acute heart failure (Pre-RELAXAHF): a multicentre, randomised, placebo-controlled, parallel group, dose-finding phase IIb study," The Lancet, vol.
The third group is comprised of the relaxin receptors LGR7 and 8.
Meuris, "The role of relaxin in the development of the uteroplacental circulation in early pregnancy," Obstetrics and Gynecology, vol.
(2012) Relaxin improves TNF-alpha-induced endothelial dysfunction: the role of glucocorticoid receptor and phosphatidylinositol 3-kinase signalling.
JosephwillwantCamelotto relaxin theearlystagesandI reckonhewill haveatleastfourorfivehorsesin frontofhimheadingdownthehill.
As the pelvic ligaments are relaxed or weakened during the birth process by relaxin and progesterone, there is more instability of the pelvic joints including pubic symphysis which sometimes lead to abnormal widening and injury followed by pain and disability.