Targeted motor and sensory reinnervation
(TMSR) is a surgical procedure on patients with amputations that reroutes residual limb nerves towards intact muscles and skin in order to fit them with a limb prosthesis allowing unprecedented control.
of recipient SS nerve (92%) demonstrated significantly better outcomes for M3 or more shoulder abduction than axillary nerve (69%).
10 One study used signal strengthening, strengthening exercises, muscle relaxation exercises, diagnostic fitting, functional and activity exercises for training amputees with targeted mucle reinnervation
Within three to nine months, reinnervation
synkinesis may develop that can result in upper airway obstruction and difficulty breathing if both recurrent nerves have been injured, depending on the proportion of adductor and abductor fibers reinnervated.
Targeted muscle reinnervation
for real-time myoelectric control of multifunction artificial arms," The Journal of the American Medical Association, vol.
The presence of groups of type-1 fibers and groups of type-2 fibers within a single sampled muscle, which is indicative of repetitive rounds of denervation and reinnervation
in muscle with neuropathic findings.
As stated above, nerve regeneration after injury is possible in the PNS and involves major events such as Wallerian degeneration, axonal degeneration, remyelination, axonal regeneration, and nerve reinnervation
Electromyography revealed signs of ongoing reinnervation
in the obturator nerve distribution and a reduced contraction pattern in the femoral and sciatic nerve musculature.
No differences in striatal [18F]DOPA uptake were observed between transplanted patients who did or did not develop GID [20, 23], suggesting that GID should not be caused by excessive growth of the grafted DA neurons, or abnormalities in striatal DA reinnervation
In conclusion, the NCV and EMG studies showed a sensory and motor neuropathy, axonal type, with signs of reinnervation
, consistent with a chronic process and severe expression.
If replenishing a healthy muscle stem cell pool facilitates reinnervation
and recovery, it would be a significant leap forward.
3) The longer a muscle is denervated, the more the probability of reinnervation
decreases, indicating the need for early evaluation, including exploration of the temporal nerve, to expedite the treatment plan and potentially improve outcomes.