regulon


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reg·u·lon

(reg'yū-lon),
A set of structural genes, all with the same gene regulation, the gene products of which are involved in the same reaction pathway.

reg·u·lon

(reg'yū-lon)
A set of structural genes, all with the same gene regulation, with gene products involved in the same reaction pathway.

regulon

(rĕg′yoo-lŏn)
A group of unrelated genes whose transcription is either suppressed or increased by a single protein.

regulon

a system where more than one structural GENE/OPERON, each with its own PROMOTER, is under control of the same regulator molecule, for example, an activator protein or repressor protein. The genes/operons collectively forming a regulon are often non-contiguous on the genome and share common regulatory sequences, such as activator binding sites (initiators) or operators (see OPERON MODEL), each of which is recognized by the same regulator molecule. A regulon may be positively controlled by an activator protein, as in the maltose regulon of ESCHERICHIA COLI, or negatively controlled by a repressor protein, as in the arginine regulon of E.coli.
References in periodicals archive ?
We identified 90 additional differentially expressed genes associated with stress regulons based on a search of RegulonDB, UniProt, and the work of others (Table S4, Figure 3) [31, 34, 35, 37-58].
The toxR regulon activates the transcription of the toxT gene, which in turn stimulates the production of proteins that activate several genes involved in virulence of V.
Our bioinformatic analyses of how LCA alters the age-related chronology of changes in the concentrations of these various mitochondrial proteins demonstrated that they belong to two regulons called a partial mitochondrial dysfunction (PMD) regulon and an oxidative stress (OS) regulon, each regulated in response to a different aspect of limited mitochondrial function (Table 1) [53, 54].
Phosphate regulon response regulator OmpR, nitrogen regulation sensor histidine kinase GlnL, and response regulator CheB are associated with two-component system pathway.
Toward the identification and regulation of the Arabidopsis thaliana ABI3 regulon. Nucl.
Upon reaching a sufficient cell density on the intestinal mucosa, the Agr-like quorum-sensing system is triggered, which in turn up-regulates the VirR/VirS regulon. This regulon includes NetB.
HrpR and HrpS proteins are involved in activation of the hrp regulon and considered as bacterial enhancer-binding proteins (bEBPs) that operate as a highly co-dependent hetero-hexameric complex (32).
In response to an SOS-inducing treatment or condition, a signal (involving regions of single-stranded DNA) is generated that stimulates expression of the SOS regulon. RecA protein binding to single-stranded DNA regions in the presence of a nucleoside triphosphate forms a nucleoprotein filament and converts RecA protein to an activated form (12).
In Ovations Holdings said it continues to pursue several potential business opportunities in the cancer-related field through its development and sale of sputum cytology and its partnership with Regulon, Inc.
The first characterization study of genes involved in the anaerobic metabolism of glycerol revealed that the dha regulon organization is present in different microorganisms capable of using glycerol as a carbon source.
WP2 Unravel the regulon of cesFSR and the role of cesF in cesR activity.
These promoter mutations result in up regulation of the whiB7 regulon, leading to an increase in eis expression and resulting KAN resistance [12].