refluxate

(rē-flŭks′āt″)

The acid, gas, and liquid that rise from the upper gastrointestinal tract into the esophagus in gastroesophageal reflux disease. Its components may include gastric acids, bile, and pepsin.

References in periodicals archive ?

The role of an alginate suspension on pepsin and bile acids - key aggressors in the gastric refluxate.

Hidden dangers of heartburn drugs

Aspiration of even a small amount of a neutral-pH refluxate causes cough," Koufman explains.

Acid reflux, asthma, and recalcitrant cough

2) LPR is linked to globus by two main mechanisms: (1) vagal reflux stimulation in the esophagus by acidic reflux and (2) mucosal injury in the larynx from direct contact with refluxate that contains gastric acid and pepsin.

Globus sensation and laryngopharyngeal reflux

18) This transition usually occurs in the context of chronic gastrooesophageal reflux disease, which causes exposure of the epithelium to refluxate.

Current management of oesophageal cancer

While many people experience some degree of normal reflux of gastric acid contents, such episodes are generally considered "physiologic," as they are asymptomatic and the refluxate rapidly clears.

Evaluation of gastroesophageal reflux and its complications

PPI therapy exclusively targets gastric acid production, but acid is not the only potentially harmful agent in the refluxate.

Treating BE better: one physician's take on combining radiofrequency therapies in a proposed algorithm for effectively treating of Barrett's esophagus, which can lead to esophageal adenocarcinoma

He then talked about nature of gastric refluxate in detail.

Patients with chronic symptoms of GERD and those with complications tend to seek medical treatment

In the first case, chemical irritants in the gastric refluxate enter the laryngopharyrnx and cause local mucosal injury.

Hoarseness and chronic cough: would you suspect reflux? Laryngopharyngeal reflux disease is often misdiagnosed as an upper respiratory infection or allergic rhinitis--or confused with GERD. This review will help you diagnose and treat it

MII with pH sensor allows the detection of acidic (pH<4), weakly acidic (4[greater than or equal to]pH<7), and weakly alkaline (pH[greater than or equal to]7) reflux and can also determine the characteristics of the gastric refluxate (gas, liquid, mixed gas and liquid).

Refractory gastro-oesophageal reflux disease: a major management issue in clinical practice: refractory gastro-oesophageal reflux disease can be frustrating, for both patient and practitioner

The nature and amount of refluxed material, as well as the length of time the refluxate remains in contact with the esophageal mucosa, determine whether disease develops.

Update on esophagitis: controversial and underdiagnosed causes

Poor esophageal peristalsis may further impair clearance of acid or non-acid refluxate, thereby explaining the persistence of symptoms despite maximal medical management.

Esophageal motility dysfunction in children with Rett syndrome, gastroesophageal reflux, and dysphagia

This study was carried out to evaluate the effect of preanaesthetic oral administration of sodium rabeprazole on pH and volume of gastric contents in adult patients undergoing elective surgery by excluding cases contaminated with duodeno-gastric refluxate.

Effect of single oral dose of sodium rabeprazole on the intragastric pH & volume in patients undergoing elective surgery