reductase


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reductase

 [re-duk´tās]
an enzyme that catalyzes a chemical reduction.
5α-reductase an enzyme that catalyzes the irreversible reduction of testosterone to dihydrotestosterone.

re·duc·tase

(rē-dŭk'tās),
An enzyme that catalyzes a reduction; because all enzymes catalyze reactions in either direction, any reductase can, under the proper conditions, behave as an oxidase and vice versa, hence the term oxidoreductase. For individual reductases, see the specific names.
Synonym(s): reducing enzyme

reductase

/re·duc·tase/ (-tās) a term used in the names of some of the oxidoreductases, usually specifically those catalyzing reactions important solely for reduction of a metabolite.
5α-reductase  an enzyme that catalyzes the irreversible reduction of testosterone to dihydrotestosterone; enzyme deficiency leads to a form of male pseudohermaphroditism.

reductase

(rĭ-dŭk′tās′, -tāz′)
n.
Any of various enzymes that catalyze the reduction of an organic compound.

reductase

A generic term for any enzyme that catalyses a chemical reduction reaction.

re·duc·tase

(rĕ-dŭk'tās)
An enzyme that catalyzes a reduction; because all enzymes catalyze reactions in either direction, any reductase can, under the proper conditions, behave as an oxidase and vice versa; hence the term oxidoreductase.

reductase

an ENZYME that catalyses the REDUCTION of a compound.

reductase

an enzyme that catalyzes a chemical reduction.
5α-reductase
an enzyme that catalyzes the irreversible reduction of testosterone to dihydrotestosterone.
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References in periodicals archive ?
Glutathione amount and form, and glutathione reductase activity in cotton did not vary in response to differential water status of the magnitude and timing imposed in this study.
Seasonal patterns of glutathione and ascorbate metabolism in field-grown cotton under water stress
This population-based case-control study suggests that the HMG-CoA reductase inhibitors, but not other lipid-lowering agents, are associated with a significantly decreased risk of subsequent fracture in humans, especially in current users.
Is exposure to HMG-CoA reductase inhibitors (statins), fibrates, or other lipid-lowering drugs associated with reduced risk of bone fracture in older patients?
Magnesium-deficient plants turned on their fercic-chelate reductase, recalls Welch, even though magnesium itself cannot be reduced by the reductase.
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The active pharmaceutical ingredient, finasteride, of Merck's Proscar[R] for BPH and Propecia[R] for male pattern baldness work by the same mechanism of 5- reductase inhibition as SuperCool[TM] Palmetto and Sperol[TM], which are natural alternatives to these drugs with fewer side effects.
Aphios Awarded United States Patent for Compositions and Methods for Inhibiting 5-Alpha Reductase
A bioactive compound known as lovastatin, found in high concentrations in the extract, successfully inhibited HMG-CoA reductase in an experiment designed to test the enzyme's activity.
Fermenting fish to reduce cholesterol
I wish to say that while I found the article intriguing in part, and scholarly, I firmly believe the same flaw is in this overview as in the article on men in Townsend a few months ago, advocating another potent drug, Clomid (clomiphene) that also isolated 5-alpha reductase as the primary, isolating factor that has to be managed reductively, sometimes with some very potent drugs.
Reductionist approach in 5-alpha reductase article
Inhibition of converting 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-coA) to mevalonate (initiating step in cholesterol biosynthesis pathway) accomplished by HMG-coA reductase is the target of drug development for hypercholesterolemic patients.
Modulating liver cholesterol metabolism by 3-iodothyronamine
nidulans strains as well as to determine the degree of toxicity of fungicides on nitrate transporter proteins and nitrate reductase enzymes in A.
EFFECT OF FUNGICIDES ON NITRATE UPTAKE AND ASSIMILATION IN ASPERGILLUSNIDULANS
The catalase activity and glutathione reductase levels were measured in erythrocytes.
The effects of copenhagen football test on glutathione reductase and catalase activity in female football players
Some strains (<1%) of MTB lack nitrate reductase and would create false results since the control would be negative and the test would therefore be invalid.
Comparative evaluation of Mycobacterium tuberculosis drug susceptibility testing between direct nitrate reductase assay and direct proportion method
It was also identified for the first time that aldo-keto reductase 1C1 (AKR1C1) enhances tumour-promoting activities and proved the enzyme blocks the effectiveness of cisplatin and other anti-cancer drugs, which can be inhibited by flufenamic acid, the researchers concluded in the paper.
Cheap drug for common cold can stop spread of cancer
Direct Nitrate Reductase Assay (NRA) was performed as described by Musa et al.
Evaluation of mycobacterium tuberculosis drug susceptibility testing by direct nitrate reductase assay

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