reduced glutathione

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re·duced glu·ta·thi·one

glutathione acting as a hydrogen donor; glutathione.

reduced glutathione

The redox form of glutathione present in red blood cells.
See also: glutathione
References in periodicals archive ?
The liposomal glutathione contains 500 mg reduced glutathione per recommended daily dose.
Hesperidin, cisplatin, proteinase K, agarose, NADPH (13nicotinamide adenine dinucleotide 3-phosphate), 5,5-dithiobis-(2-nitrobenzoic acid) (DTNB), glutathione reductase, 2thiobarbituric acid (TBA), glutathione peroxidase, reduced glutathione (GSH), glutathione oxidized (GSSG), catalase, 2,7-dichlorofluorescein diacetate (DCFH-DA), caspase 3 assay kit, fluorimetric, superoxide dismutase assay kit, Bradford reagent, O-dianisidine, HTAB (hexadecyl trimethyl ammonium bromide), etc.
4] Nonstandard abbreviations: CysGly, cysteinylglycine; GSH, reduced glutathione ([gamma]-L-glutamyl-L-cysteinylglycine); Hcy, homocysteine; PHMB, p-hydroxymercuribenzoate; DTT, dithiothreitol; GSNO, nitrosoglutathione; GSSG, glutathione disulfide; TFA, trifluoroacetic acid; RPC, reversed-phase chromatography; DCM, dilated cardiomyopathy; DAD, diode array detector; CVGAFS, cold vapor generation atomic fluorescence spectrometry; and LODc, concentration detection limit.
The highly reduced sugar 2-deoxy-D-ribose induces apoptosis in human fibroblasts by reduced glutathione depletion and cytoskeleton disruption.
BCCA caused significant depletion in superoxide dismutase (SOD), glutathione peroxidase (GPx), reduced glutathione (GSH), catalase (CAT), glutahione-S-transferase (GST), glutathione ruductase (GR) and significant increase in malondialdehyde (MDA) in brain.
The Nathan/Van Konynenburg studies showed the following in plasma from ME/CFS patients: Initial levels before therapy was initiated showed all four reduced folates studied, including 5-methyltetrahydrofolate (5-MTHF); tetrahydrofolate and folinic acid were all low in CFS patients; S-adenosyl methionine (SAM) was modestly low (circa 10%); reduced glutathione (GSH) was low; and GSH/GSSG (oxidized glutathione) was low.
The liver, kidney and brain were assayed for the degree of lipid peroxidation, reduced glutathione content and the activity of enzymic and levels of non-enzymic antioxidants.
Reduced glutathione (GSH) is ubiquitous and abundant; it can be oxidized to its disulfide form (GSSG) in response to an oxidative perturbation.
2008b), and myeloperoxidase (MPO) and a simultaneous decrease in the ratio of reduced glutathione (GSH) to oxidized glutathione (GSSG) (Rahman and Adcock 2006).
Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: a randomized double-blind placebo-controlled trial.
RESULTS: An increase in the activity of glutathione reductase (GR), superoxide dismutase (SOD), reduced glutathione (GSH) and malondialdehyde (MDA) in the lysates of erythrocytes was seen after two days of exposure from 131I radiations.

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