reconstructed ion chromatogram

reconstructed ion chromatogram

A normal mass spectrometric data set consisting of full mass spectra recorded sequentially in time as a sample is passed to the ion source, either from a direct-insertion probe or from a chromatograph (e.g., GC/MS). The total ion current trace is the sum of ion abundances in each mass spectrum plotted vs time.

Each spectrum contains a pattern of molecular ions and fragment ions, which can be specified, and data plotted of scan-by-scan abundance of specific ions vs time—the so-called reconstructed ion chromatogram (RIC). The RIC can be used to identify all ions belonging in a single mass spectrum, based on their coincident peaks in time, while discriminating against background ions, and can be used to screen a GC/MS run for related classes of compounds by re-constructing ion chromatograms for common structurally specific ions.
References in periodicals archive ?
Abstract: Mass spectra of reconstructed ion chromatogram (MRIC) technique are used to follow up the grafting copolymerization of 1-vinyl-2-pyrrolidinone (VP) 1-vinyl-3-anisylidine-2-pyrrolidinone (VAP) and ethylmethacrylate (EMA) and cellulose extracted from kenaf using xanthate method.
3, B, D, and F, shows reconstructed ion chromatograms (RICs) appropriate to monohydroxycholesterols and hydroxycholest-4-en-3-ones (HC/HCO, m/z 539.
Reconstructed ion chromatograms of a blank plasma enriched with IS and therapeutic concentrations of all 8 sulfonylureas are shown in Fig.