recombinase


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recombinase

(rē-kŏm′bə-nās′, -nāz′)
n.
An enzyme that catalyzes the exchange of short pieces of DNA between two long DNA strands, particularly the exchange of homologous regions between the paired maternal and paternal chromosomes.

recombinase

(rē-kŏm′bĭn-ās) [ recombinan(t) + ″]
Any enzyme that catalyzes nucleic acid recombination, i.e., the rearrangement of genetic material on a strand of DNA or RNA.

recombinase

a function of the recA protein in Escherichia coli that catalyzes the binding and unwinding of the double strands of DNA that form a synapse during DNA recombination.
References in periodicals archive ?
Site-specific recombinase (Hin) enzyme is required for DNA segment inversion.
This agent, called key, will inhibit the repressor action over the recombinase gene, allowing its expression, which will unlock the expression the gene of interest.
After creating circuits that could record events, the researchers then incorporated genes into the array of recombinase binding sites, along with genetic regulatory elements.
Recombinase polymerase Specificity of 100% (95% 2014 [42] amplification: a CI, 92%-100%) and a recombinase complex from sensitivity of 83% (95% T4 bacteriophage CI, 51%-97%) Detection introduces primers to limit of 5 to 12 specific DNA sites to pathogens per test initiate an amplification reaction by the strand, displacing DNA polymerase.
For the first time ever researchers use an especially fast detection reaction in the droplets, known as recombinase polymerase amplification, reducing the time necessary for the procedure from over two hours to less than 30 minutes.
Researchers developed a genetically modified mouse in which the Hif-1alpha protein is fused to another protein, called Cre recombinase, which could then be used for cellular labeling.
On the other hand, BRCA1 interacts with RAD51 recombinase (RAD51) during homologous recombination mediated DNA double-strand break repair forming a nucleoprotein filament on DNA and its mutation can increase the risk of breast cancer (9-11).
Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC.
flox/flox] mice: To specifically investigate the role of each Fgfr1 and Fgfr2 in germ cells, a transgenic Cre mouse line expressing an improved Cre (iCre) recombinase driven by the mouse Tex101 promoter (Tex101-iCre) was used.
Mosaic staphylococcal cassette chromosome mec containing two recombinase loci and a new mec complex, B2.
Cre recombinase expression is controlled by Osterix1 (Osx1) promoter (Osx is a gene which differentially expresses at the earlier stages of osteoblast) (25).
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