reciprocal translocation


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translocation

 [trans″lo-ka´shun]
the attachment of a fragment of one chromosome to a nonhomologous chromosome.
Translocation of a portion of one chromosome to another chromosome. Redrawn from Damjanov, 2000.
reciprocal translocation the mutual exchange of fragments between two broken chromosomes, one part of one uniting with part of the other.
robertsonian translocation that in which the breaks occur at the centromeres and entire chromosome arms are exchanged, usually involving two acrocentric chromosomes.

re·cip·ro·cal trans·lo·ca·tion

translocation without demonstrable loss of genetic material.

re·cip·ro·cal trans·lo·cation

(rĕ-sip'rŏ-kăl tranz'lō-kā'shŭn)
Translocation without demonstrable loss of genetic material.
References in periodicals archive ?
The balanced reciprocal translocations (BRTs) can be identified by conventional cytogenetic techniques but the cryptic or terminal translocations are difficult to identify.
The prevalence of reciprocal translocations in the general population is about 1/625.
There is a significant increased risk of giving birth to a child with Trisomy 21 when one parent is a Robertsonian translocation carrier or of reciprocal translocations as they may produce balanced and unbalanced gametes during gametogenesis.
Of the 9207 infertile males reviewed (8) 6 per cent were carriers of a reciprocal translocation and 0.8 per cent of a Robertsonian translocation, which is respectively 6.5 and 9.4 times higher than in newborns series (8).
In addition, 38 (50%) of the chimeric reads were mapped to each of the resulting derivative chromosomes, supporting the presence of a reciprocal translocation event.
Reciprocal translocation is the most common chromosomal abnormality found in 1 in 500 people (11).
SchulzSchaeffer and Friebe (1992) reported a reciprocal translocation between chromosomes 1B and 2B in MT-2.
Lambert et al (22) first described a reciprocal translocation t(1; 10)(p22; q24) in MIFS, which had a complex karyotype and deletions of chromosomes 3 and 13.
The reciprocal translocation involving the bcl-2 locus on chromosome 18q21 and the immunoglobulin heavy chain locus (IgH) on chromosome 14q32 is shown schematically in Fig.
Either a paracentric inversion of chromosome 10, or a reciprocal translocation between chromosomes 10 and 17, result in a RET/PTC fusion gene, placing the tyrosine kinase domain of RET (usually constitutively silent in follicular cells) under the transcriptional control of constitutively active genes.
Reciprocal translocation t(12; 22)(q13;q13) in clear cell sarcoma of tendons and aponeuroses.
Several subtypes of human acute leukemia are associated with reciprocal translocations of the Myeloid Lymphoid Leukemia (MLL) gene which fuses to more than 50 different loci.