receptor modulator


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receptor modulator

n.
A substance that acts on a chemical receptor, usually as an agonist, antagonist, or combination of both: a selective estrogen receptor modulator; a nicotine receptor modulator.
References in periodicals archive ?
Exposure-response analysis to assess the safe and efficacious dose of the selective progesterone receptor modulator vilaprisan (VPR) for the treatment of patients with uterine fibroids presented by Bart Ploeger (in the oral presentation session Gynecology: Myoma and Endometriosis on Friday, October 20, 2017: 05:00 PM to 06:30 PM Room B.
Progesterone receptor modulator CDB-2914 down-regulates vascular endothelial growth factor, adrenomedullin and their receptors and modulates progesterone receptor content in cultured human uterine leiomyoma cells," Human Reproduction 21 (9): 2408-2416.
Today, several medications are available for the prevention or treatment of osteoporosis, such as Evista (raloxifene), a selective estrogen receptor modulator, or SERM, which is protective against vertebral fractures.
Memory Pharmaceuticals, co-founded by Nobel laureate Eric Kandel, is developing a calcium channel receptor modulator that increases the sensitivity of neurons and allows them to transmit information more speedily and a nicotine receptor modulator that plays a role in synaptic plasticity.
Bristol-Myers was developing a thyroid hormone receptor modulator for the treatment of obesity.
NEW ORLEANS -- The selective estrogen receptor modulator raloxifene may improve antidepressant response in postmenopausal women with treatment-resistant depression, according to preliminary findings reported in a poster presentation at the annual meeting of the American Psychiatric Association.
Many companies hope to develop a designer estrogen, or selective estrogen receptor modulator (SERM), that men can take to prevent heart disease.
Ostarine (GTx-024) is a first in class selective androgen receptor modulator, or SARM, which GTx is evaluating for the treatment of cancer cachexia (muscle loss).
Ralinepag is a Phase 3-ready next-generation, oral, selective prostacyclin receptor (IP) agonist for the treatment of pulmonary arterial hypertension (PAH), and etrasimodis a Phase 2 oral, next-generation, S1P receptor modulator, that is being evaluated for multiple autoimmune diseases, including ulcerative colitis.
Ospemifene, a novel selective estrogen receptor modulator for treating dyspareunia associated with postmenopausal vulvar and vaginal atrophy.
Sermonix is excited to partner with Ligand on lasofoxifene, a best-in-class selective estrogen receptor modulator, or SERM, and to seek regulatory approval of this remarkable drug," said David Portman, M.
Tokyo, Japan, June 30, 2006 - (JCN) - Eisai announced June 29 that it signed a license agreement with Radius Health, headquartered in Massachusetts, for the use of Eisai's new class of selective estrogen receptor modulator (SERM).

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