"That just shows there may be a rebound effect
when you have a statin on board and you are controlling your LDL cholesterol production through the liver," said Zaric, who wasn't part of the study.
We're currently looking at the 'rebound effect
' of energy efficiency measures in industry.
That's what we call 'the rebound effect
' - which is also noticeable in people who take a lot of sleeping pills.
Upon discontinuing denosumab, there's a marked rebound effect
in which levels of bone turnover markers rise for 2 years, and some or all of the BMD that was gained is lost (J Clin Endocrinol Metab.
'Many people think alcohol is a good inducer of sleep, but there's a rebound effect
,' said senior study author Dr Jose Ordovas, a researcher at CNIC and a senior scientist at Tufts University.
"They were well beaten last week, so there'll be a rebound effect
from that," said Healy.
Following treatment cessation, less than 1 percent of patients experienced a rebound effect
The widespread use of aspirin and the possibility of a rebound effect
with discontinuation highlights a need for more research.
Medicated nasal sprays, meanwhile, contain active ingredients such as oxymetazoline hydrochloride or fluticasone propionate which is a well-established cause of "rebound effect
" in which the more of it a person uses the more one needs to use in order to get the same effect.
Denosumab discontinuation is associated with a rebound effect
which manifests by a severe increase of bone turnover markers and a rapid loss of BMD.
At present, the most common are the rebound effect
, free riders, and spillover effects.