reagin

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Related to reagin: reign, cardiolipin, VDRL test

reagin

[re´ah-jin]

antibody of a specialized immunoglobulin class (IgE) which attaches to tissue cells of the same species from which it is derived, and which interacts with its antigen to induce the release of histamine and other vasoactive amines. A form of cytotropic antibody, it is present in the serum of naturally hypersensitive individuals and can confer specific immediate (type I) hypersensitivity in nonreactive individuals. adj., adj reagin´ic.

re·a·gin

(rē-ā'jin),

1. Wolff-Eisner term for antibody.

2. Old term for the "Wassermann" antibody; not to be confused with the Prausnitz-Küstner antibody.

3. Antibodies that mediate immediate hypersensitivity reactions (IgE in humans).

4. Synonym(s): homocytotropic antibody

reagin

(rē-ā′jĭn)

1. An antibody found in the blood of individuals having a genetic predisposition to allergies.

2. A substance present in the blood of individuals having a positive serological test for syphilis.

re′a·gin′ic (rē′ə-jĭn′ĭk) adj.

re′a·gin′i·cal·ly adv.

re·a·gin

(rē-ā'jin)

1. Wolff-Eisner term for antibody.

2. Antibodies that mediate immediate hypersensitivity reactions (IgE in humans).

3. Synonym(s): homocytotropic antibody.

References in periodicals archive ?

Bailey, "Performance of the rapid plasma reagin and the rapid syphilis screening tests in the diagnosis of syphilis in field conditions in rural Africa," Sexually Transmitted Infections, vol.

Comparison of RPR and ELISA with TPHA for the Diagnosis of Syphilis: Implication for Updating Syphilis Point-of-Care Tests in Ethiopia

Yes 170 8.9 No 1213 63.7 Do not know 522 27.4 Total 1905 100 Abbreviations: CLIA, Clinical Laboratory Improvement Amendments; CMIA, chemiluminescent microplate immunoassay;EIA, enzyme immunoassay; FTA-ABS, fluorescent treponemal antibody absorption test;TP-LIA, Treponema pallidum line immunoassay;MHA-TP, micro-hemagglutination assay for Treponema pallidum antibodies;PK-TP, Olympus automated hemagglutination test;RPR, rapid plasma reagin assay; TP-PA, Treponema pallidum particle agglutination assay; VDRL, venereal disease research laboratory test;USR, unheated serum reagin test.

Prevalence of Traditional and Reverse-Algorithm Syphilis Screening in Laboratory Practice: A Survey of Participants in the College of American Pathologists Syphilis Serology Proficiency Testing Program

Abbreviations: RPR = rapid plasma reagin, TPHA = Treponema pallidum hemagglutination, CIA = chemiluminescence immunoassay, FTA-ABS = fluorescent treponemal antibody-absorption, EIA = enzyme immunoassay, LIA = line immunoassay; ID = indeterminate.

Serological diagnosis of syphilis: a comparison of different diagnostic methods

However the rapid plasma reagin (RPR) was reactive at 1:16 titration.

Syphilis in pregnancy

Maternal characteristics for CMV-infected and -uninfected neonates CMV- CMV- p-value negative, positive, n=62 n=24 Age (years), n 0.95 <20 12 4 20-35 42 17 >35 8 3 Parity (n) 0.78 <2 48 18 2-4 13 5 >4 1 1 Mode of delivery, n (%) 0.57 Vaginal 34 (55) 15 (63) Caesarean 27 (44) 9 (37) Unknown 1 (1) 0 (0) RPR, n (%) 0.10 Positive 5 (8) 1 (4) Negative 57 (92) 23 (96) HIV, n (%) 0.003 Positive 27 (43) 19 (79) Negative 35 (57) 5 (21) CMV = cytomegalovirus; RPR = rapid plasma reagin. Table 3.

Characteristics and mortality rate of neonates with congenital cytomegalovirus infection

Reagin, while at United Medical Center, Washington, DC; and Dr.

Photon-counting digital mammography detects rare breast lesion

the rapid plasma reagin (RPR) test, are unreliable in detecting the disease in psychiatric patients.

Syphilis sero-positivity in recently admitted and long-term psychiatric inpatients: screening, prevalence and diagnostic profile

(3) In another study, 40% of 206 leprosy patients had reactive results for the VDRL or rapid plasma reagin (RPR) tests, both non-treponemal serological tests for syphilis.

Nodular secondary syphilis simulating lepromatous leprosy

Methods: We administered a structured questionnaire and obtained a blood sample for syphilis serology (rapid plasma reagin test with Treponema pallidum hemagglutination assay confirmation) from all women giving informed consent over six weeks in 2007.

Prevalence of syphilis among antenatal clinic attendees in Karachi: Imperative to begin universal screening in Pakistan

These tests, also referred to as phospholipid antibody tests, use various techniques, such as flocculation tests or enzyme-linked immunosorbent assays (ELISA), in order to detect antibodies that target reagin, which is a complex of cardiolipin, lecithin, and cholesterol.

A review of the biology and the laboratory diagnosis of Treponema pallidum infections

Antenatal blood test results showed that the mother was Rhesus positive, the rapid plasma reagin (RPR) for syphilis was negative, and she was HIV-positive (she was receiving treatment).

A severe case of astrogliosis and encephalomalacia in a neonate with a massive vein of Galen malformation (VGM)

El 23/04/09, la orina fue normal; el 29/04/09, la prueba reagin protein reactive fue negativa, aglutinaciones a brucella no reactivas, antigeno de hepatitis de superficie (HBsAg) no reactivo, virus de la inmunodeficiencia humana (VIH, metodo Elisa) no reactivo (05/05/09), prueba de Coombs directa negativa.