reagin


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reagin

 [re´ah-jin]
antibody of a specialized immunoglobulin class (IgE) which attaches to tissue cells of the same species from which it is derived, and which interacts with its antigen to induce the release of histamine and other vasoactive amines. A form of cytotropic antibody, it is present in the serum of naturally hypersensitive individuals and can confer specific immediate (type I) hypersensitivity in nonreactive individuals. adj., adj reagin´ic.

re·a·gin

(rē-ā'jin),
1. Wolff-Eisner term for antibody.
2. Old term for the "Wassermann" antibody; not to be confused with the Prausnitz-Küstner antibody.
3. Antibodies that mediate immediate hypersensitivity reactions (IgE in humans).

reagin

/re·a·gin/ (re´ah-jin) the antibody that mediates immediate hypersensitivity reactions; in humans, IgE.reagin´ic

reagin

(rē-ā′jĭn)
n.
1. An antibody found in the blood of individuals having a genetic predisposition to allergies.
2. A substance present in the blood of individuals having a positive serological test for syphilis.

re′a·gin′ic (rē′ə-jĭn′ĭk) adj.
re′a·gin′i·cal·ly adv.

reagin

[rē′ājin]
Etymology: L, re + agere
1 an antibody associated with human atopy, such as asthma and hay fever. It attaches to mast cells and basophils and sensitizes the skin and other tissues. In antigen-antibody reactions it triggers the release of histamine and other mediators that cause atopic symptoms.
2 a nonspecific, nontreponemal antibody-like substance found in the serum of individuals with syphilis. It can combine with an antigen prepared as a lipid extract of normal tissue, a phenomenon that constitutes the basis of the serological tests for syphilis. reaginic, adj.

re·a·gin

(rē-ā'jin)
1. Wolff-Eisner term for antibody.
2. Antibodies that mediate immediate hypersensitivity reactions (IgE in humans).
3. Synonym(s): homocytotropic antibody.

reagin

an old term for immunoglobulin E antibody (IgE).

atopic reagin
the antibody responsible for hypersensitivity reactions to specific substances with signs of atopy resulting.
References in periodicals archive ?
Rapid Plasma Reagin (RPR) result for the baby was non- reactive.
Laboratory analysis: Blood samples were tested by rapid plasma reagin (RPR) card test (Randox kit).
During the VDRL test, patient serum is mixed with the reagin antigen solution.
Reagin attributes politicization to the intense dearth in wartime Germany and to the increasing influence of housewives' associations affiliated with conservative political parties.
By Nancy Reagin (New York and Cambridge: Cambridge University Press, 2007.
rapid plasma reagin (RPR)) and cerebrospinal examination were not routinely done for these infants.
They also received an HIV and rapid plasma reagin (RPR) test for syphilis if they had suspicious symptoms, had not been tested for more than 1 year, had another sexually transmitted infection, had sold sex, or requested testing.
pallidum; de tipo IgA, IgM o IgG, entre los cuales estan: Inmunoanalisis Enzimatico (ELISA), Hemaglutinacion Indirecta del Treponema (TPHA), Inmunocromatografia (IC), Absorcion de Anticuerpos Treponemicos Fluorescentes (FTA-abs), y las pruebas inespecificas dirigidas a la determinacion de anticuerpos no treponemicos que son liberados por el tejido necrotizado de la lesion, entre los mas utilizados se encuentran: Venereal Disease Research Laboratory (VDRL), Prueba Rapida de Reaginas Plasmaticas (RPR), Undeated Serum Reagin (USR) (1,3-6).
The Rapid Plasma Reagin for syphilis was reactive with a 1:1 titre; Treponema passive particle agglutination and syphilis enzyme immune assay were also reactive suggesting either latent, previously treated or early treponemal infection.
Nancy Reagin brings her extensive knowledge of women's social history to bear on the issues of nation building and nationalism that have traditionally been considered a domain of male actors.
Today, the Rapid Plasma Reagin (RPR) and Venereal Disease Research Laboratory test, as well as other tests based on monoclonal antibodies and immunofluorescence, are used to diagnose syphilis.