reading frame


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read·ing frame

(rēd'ing frām),
The grouping of nucleotides by threes into codons. See: frameshift mutation.

reading frame

n.
One of the three possible ways in which an mRNA sequence of nucleotides can be read as a series of base triplets to specify the amino acids in a protein chain.

reading frame

An imaginary window through which base pairs can be inspected three at a time, and which provides a way in which a nucleotide sequence can be viewed as three different sets of CODONs only one of which is correct.
References in periodicals archive ?
FP, cells with both shRNAs for 3D and ORF7; f, 3D gene expression vector; p, ORF7 expression vector; fp, both vectors above; CD163, cluster of differentiation 163; ORF, open reading frame.
Read mappings from the (A) Templiphi-generated muscle library for the coI open reading frame, (B) nd4 open reading frame, (C) D-loop, and (D) nd6 open reading frame.
It includes a CpG-rich bidirectional promoter and 2 open reading frames for ORF1p and ORF2p proteins.
The extracted features of Lncident can be divided into two categories: open reading frame (ORF) features and fc-mer adjoining-base(s) features from sequence intrinsic composition.
Onate, "Evaluation of protective effect of DNA vaccines encoding the BAB1 0263 and BAB1 0278 open reading frames of Brucella abortus in BALB/c mice," Vaccine, vol.
The Comp16495 contig (GenBank KF717090) was 2,097 bp long, with an open reading frame encoding 680 amino acids.
Analysis of the fusion sequence revealed an open reading frame encoding a protein of 445 amino acids with predicted molecular mass of about 50 kDa without glycosylation (ExPASy).
In case of the frame-shifting deletion of exon, modifying the splicing of mRNA allows the exclusion of one or several additional exons and the restoration of a reading frame (Figure 5).
Genotype-phenotype correlation studies in D/BMD have shown that the disease severity is influenced not so much by the size of the mutation, as by: (i) the location of the mutation in relation to the critical functional domains of the dystrophin protein; and (ii) the effect of the mutation on the DNA translational open reading frame (ORF).
Molecular analysis of partial open reading frame V1 sequences showed that PiCV strains detected in feral pigeons share high nucleotide and amino acid sequence identities with PiCV strains detected in ornamental, racing, meat, and feral pigeons.
What we know and love, reading Frame, are the dizzying effects of re-enactments, mimicry and echoing; the work patterning like the figure in a trick-mirror box infinitely, recognisably, yet increasingly estranged.
Other mutation types such as a change from an amino acid to a stop codon, a mutation that results in a shift of the reading frame, and changes that affect the process of splicing, result in premature termination of translation with possible nonsense-mediated mRNA decay and are highly likely to be deleterious.