reading frame


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read·ing frame

(rēd'ing frām),
The grouping of nucleotides by threes into codons. See: frameshift mutation.

reading frame

n.
One of the three possible ways in which an mRNA sequence of nucleotides can be read as a series of base triplets to specify the amino acids in a protein chain.

reading frame

An imaginary window through which base pairs can be inspected three at a time, and which provides a way in which a nucleotide sequence can be viewed as three different sets of CODONs only one of which is correct.

reading frame

the actual codons that are translated (read) during mRNA synthesis. In principle a DNA sequence can be transcribed in any one of three different reading frames, each of which will specify a completely different polypeptide. Usually only one of the three reading frames is transcribed.

open reading frame (ORF)
an extended sequence in mRNA that is free of stop codons.
References in periodicals archive ?
The open reading frame encoded a 255 amino acid residue protein with an isoelectric point (pI) of 5.
Read mappings from the (A) Templiphi-generated muscle library for the coI open reading frame, (B) nd4 open reading frame, (C) D-loop, and (D) nd6 open reading frame.
For example, the deletions of exon 46 or 44 both shift the reading frame and result in no dystrophin production.
The probable effect of the exonic changes on the ORF was predicted using the Reading Frame Checker (http: //www.
A detailed analysis of that deletion reveals that it causes a shift of the reading frame and expands over the GT donor splice site of intron 5.
Su genoma consta de RNA de cadena sencilla, de aproximadamente 15kb y contiene ocho genes u ORF (Open Reading Frame o Marcos de Lectura Abierta).
In general, mutations that maintain the reading frame are associated with BMD, whereas deletions and duplications tend to disrupt the reading frame inDMD(8, 9).
But by the time one has finished reading Frame of Art, it seems not strange at all that the fictional Clarissa and Julie would be in conversation with the real Kames, Price, and others.
That is, I want to use pornography not as a generic descriptor, but as a reading frame for mainstream Hollywood film.
Degussa AG (Dusseldorf, Germany) has patented Coryneform bacteria which have, in addition to at least one copy, present at the natural site (locus), of an open reading frame (ORF), gene or allele which codes for the synthesis of a protein or an RNA, in each case a second, optionally third or fourth copy of this open reading frame (ORF), gene or allele at in each case a second, optionally third or fourth site in a form integrated into the chromosome and processes for the preparation of chemical compounds by fermentation of these bacteria.
The linked interactive views of mass spectrometry-based proteomics data allow the user to view empirical evidence of peptides (and therefore proteins) in the context of the genome and proposed open reading frame (ORF) location.
The PDS gene (SLC26A4) has been linked to chromosomal region 7q31 and contains an open reading frame of 2,343 bp encompassing 21 exons (Coyle et al.