Iron deficiency may lead to reactive thrombocytosis
Group 2 patients are .evaluated for primary thrombocytosis and other causes of reactive thrombocytosis and those with other disorders causing reactive thrombocytosis were also excluded.
Compared to primary thrombocytosis such as that caused by essential thrombo-cythemia, reactive thrombocytosis is generally regarded as benign (3).
In contrast to patients with myeloproliferative disorders, patients with reactive thrombocytosis
usually have normal platelet function.
First of all causes of thrombocytosis such as Reactive Thrombocytosis were excluded.
The B criteria: B1: No cause for Reactive Thrombocytosis, B2--No evidence of Iron deficiency, B3--No Evidence of polycythemia vera, B4-No evidence of C.
To estimate the incidence of reactive thrombocytosis among febrile children.
The incidence of reactive thrombocytosis was 20.7% and of these 28.6% was due to serious bacterial infection.
In reactive thrombocytosis
the size and function of platelets are normal in nature and, as such, their interactions with the vessel wall should remain qualitatively normal, making thrombotic and bleeding complications less likely than in patients with essential thrombocythaemia (1,3).
According to the WHO (1), diagnosis requires a persistent platelet count [greater than or equal to] 450 x [10.sup.9]/L; examination of a bone marrow specimen to demonstrate the characteristic abnormalities of the megakaryocytic lineage; and exclusion of reactive thrombocytosis
, polycythemia vera, primary myelofibrosis, chronic myelogenous leukemia, myelodysplastic syndrome or other myeloid neoplasm.
Which of the following findings would exclude a diagnosis of reactive thrombocytosis
Platelet parameters and aggregation in essential and reactive thrombocytosis
. Am J Clin Pathol 1988;90:431-6.