reactive changes

reactive changes

term in the Bethesda classification system for reporting cervical/vaginal cytologic diagnosis that refers to changes benign in nature, associated with inflammation (including typical repair), atrophy with inflammation, radiation, an intrauterine device, and other nonspecific causes.
See also: Bethesda system, AGUS, LSIL, HSIL.

re·ac·tive chang·es

(rē-ak'tiv chānj'ĕz)
Term in the Bethesda classification system for reporting cervical or vaginal cytologic diagnoses that refers to changes of a benign nature, which are associated with inflammation (including typical repair), atrophy with inflammation, radiation, an intrauterine device, and other nonspecific causes.
See also: Bethesda system, AGUS, LSIL, HSIL
References in periodicals archive ?
Reactive changes due to underlying CKD and inflammation were the most frequent findings in the BM of the patients.
Bates et al [13] found reactive changes in 41% of HIV aspirates.
Familiarity with the histologic changes that occur in reactive lymph nodes is important in preventing misdiagnosis of lymphoma, just as awareness of the histologic changes that lymphoid neoplasms share with reactive changes is key to not missing a diagnosis of lymphoma.
The most frequent finding on histopathological analysis was reactive changes (27.
Recent studies have supported the hypothesis that astrocytes have a beneficial role contributing to amyloid-beta clearance, but also that excess amyloid-beta can lead to oxidative stress and damage, and as a consequence to reduced astrocyte functionality, leading to reactive changes and decreased neuronal support, and thereby contributing to neurodegeneration.
US and cystoscopy after 3 months showed marked regression and biopsies showed nonspecific reactive changes.
When smear microscopy identified changes in the cells it was difficult to differentiate between reactive changes and epithelial dysplasia (ASC-US); these changes were more often in the background of the inflammatory process (Figure 1).
Biopsy of the liver explant revealed intense lobular inflammation with the hepatocellular reactive changes persisting and stage IV fibrosis (Figure, panels E, F).
Frequent reactive changes - with no consideration of whole strategy
Vocal fold nodules and polyps represent reactive changes of the laryngeal mucosa and adjacent stroma that result in benign nodular or polypoid growths.
In addition, in this study it has been supposed that reactive changes could also derive from an entrepreneur's reaction to a particular internal or external condition, regardless of a previous relationship.
The dense fibrous connective tissue showed reactive changes including fibroblast proliferation, neuronal proliferation and chronic inflammation (Fig.

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