reactive changes

reactive changes

term in the Bethesda classification system for reporting cervical/vaginal cytologic diagnosis that refers to changes benign in nature, associated with inflammation (including typical repair), atrophy with inflammation, radiation, an intrauterine device, and other nonspecific causes.
See also: Bethesda system, AGUS, LSIL, HSIL.

re·ac·tive chang·es

(rē-ak'tiv chānj'ĕz)
Term in the Bethesda classification system for reporting cervical or vaginal cytologic diagnoses that refers to changes of a benign nature, which are associated with inflammation (including typical repair), atrophy with inflammation, radiation, an intrauterine device, and other nonspecific causes.
See also: Bethesda system, AGUS, LSIL, HSIL
References in periodicals archive ?
CEO McKenzie continually refused to abandon his claims to $3 million in change in control payments (to which we do not believe he was entitled) and instead of focusing on shareholders first and foremost and resolving this issue with us, the Board chose to act unilaterally without Lone Star Value and announce reactive changes to its composition.
Frequent reactive changes - with no consideration of whole strategy
Vocal fold nodules and polyps represent reactive changes of the laryngeal mucosa and adjacent stroma that result in benign nodular or polypoid growths.
In addition, sections of deep white matter from the left frontal lobe showed a small number of lesions, each consisting of a single larval nematode surrounded by mild chronic reactive changes and inflammation (macrophages, lymphocytes, plasma cells, and rare eosinophils) (Figure, panel A).
The dense fibrous connective tissue showed reactive changes including fibroblast proliferation, neuronal proliferation and chronic inflammation (Fig.
The authors cover basic cytology principles, basic anatomy and cytology of the female genital tract, the Bethesda system, liquid- based preparations, physiological cytology, reactive changes and organisms, human papillomavirus in cervical carcinogenesis, atypical squamous cells, low grade and high grade squamous intra-epithelial lesions, invasive squamous carcinoma, endocervical lesions, endometrial lesions, metastic tumors, therapy-related changes, artifacts, contaminants and incidental findings.
Separation of dysplastic cells from degenerating cells and cells undergoing non-specific reactive changes is problematic.
These would include various reactive changes associated with inflammation or intrauterine devices, hyperkeratosis or parakeratosis, and organisms such as trichomonas vaginalis, or a "shift in vaginal flora consistent with bacterial vaginosis.
Other sections cover general features, constitutional disorders, reactive changes, and clonal disease.
There may be difficulty in separating dysplastic cells from non-specific reactive changes and degenerating cells or variation in diagnostic criteria.
Also, The AutoPap was equivalent to Current Practice in identifying Satisfactory But Limited By (SBLB) slides, in identifying unsatisfactory slides, and detecting Benign Cellular Changes (BCC), reactive changes, and infection.

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