Sensitivity was 86.2% for the single rapid antigen test
, 91.4% for the combination of both antigen tests, and 95.7% for the combination of rapid antigen test
Multiple blood, urine, and sputum cultures were unrevealing; rapid antigen test
was positive for influenza A, with subsequent confirmation at the CDPH VRDL for novel influenza A (H1).
He recommended using a culture rather than a rapid antigen test
or not testing at all to confine antibiotic use.
The overall sensitivity of rapid antigen tests
for group A streptococcus has declined in recent years.
On the other hand, commercially available rapid antigen tests
such as Directigen Flu A+B (Becton Dickinson, Sparks, NJ, USA) or Binax NOW (Binax Inc., Portland, ME, USA) are rapid and simple, but subtyping of viruses is not feasible.
They also had to have a positive rapid antigen test
for Group A beta-hemolytic streptococcus (GABHS).
Elevated antistreptolysin-O (ASO) or anti-DNase B titers or evidence of GAS in the pharynx via a rapid antigen test
or throat culture are indications to try empiric GAS therapy If the urticaria goes away and stays away, you've solved the problem.
In addition, 52 (13%) of the 388 physicians who reported using the rapid antigen test
said they did not confirm a negative result with throat culture, as the clinical guidelines recommend.
Recently a high-sensitivity rapid antigen test
has become available.
For adults, guidelines that recommend against testing those with a low clinical likelihood of GAS infection and against using throat culture to confirm negative rapid antigen test
results could lead to a substantial number of missed GAS pharyngitis cases, while selective use of throat cultures is compatible with a goal of reducing antibiotic use and unnecessary prescribing of antibiotics.
However, with the current commercial availability of a rapid antigen test
with sensitivity equivalent or superior to BAP culture,[17,18] these recommendations have been challenged.[18,19]
A nasopharyngeal swab was positive for influenza A virus by a rapid antigen test
, and treatment with oseltamivir was initiated.