raphe nucleus


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raphe nucleus

Any of a set of midline reticular nuclei in the midbrain and hindbrain tegmentum that send serotonergic axons widely throughout the forebrain brain via the medial forebrain bundle. Raphe nuclei appear to regulate sleep and aggressive behavior and to influence pain perception.
See also: nucleus
References in periodicals archive ?
Anxiolytic-like effects of median raphe nucleus lesion in the elevated T-maze.
Effects of inactivation of serotonergic neurons of the median raphe nucleus on learning and performance of contextual fear conditioning.
Dorsal raphe nucleus serotonergic neurons innervate the rostral ventrolateral medulla in rat.
When the pathway between the prefrontal cortex and the dorsal raphe nucleus was stimulated, rodents facing a challenge in the lab showed an immediate and dramatic surge in motivation.
1A] receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats.
Increased REM sleep after intra-dorsal raphe nucleus injection of flesinoxan or 8-OH-DPAT: prevention with WAY 100635.
Keywords: Xanthone Serotonin Kielmeyera coriacea Median raphe nucleus Forced swimming test
In light of the above, this study investigated the effect on the intra-median raphe nucleus (MRN) of injection of xanthone obtained from Kielmeyera coriacea stems, and compared with drugs that selectively interfere with the activity of MRN serotonergic neurons, the 5-[HT.