raphe nucleus


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raphe nucleus

Any of a set of midline reticular nuclei in the midbrain and hindbrain tegmentum that send serotonergic axons widely throughout the forebrain brain via the medial forebrain bundle. Raphe nuclei appear to regulate sleep and aggressive behavior and to influence pain perception.
See also: nucleus
References in periodicals archive ?
Group Anatomic structure B1 Raphe pallidus nucleus, caudal ventrolateral medulla B2 Raphe obscurus nucleus B3 Raphe magnus nucleus, rostral ventrolateral medulla B4 Dorsolateral raphe obscurus dorsolateral B5 Median raphe nucleus, caudal part B6 Dorsal raphe nucleus, caudal part B7 Dorsal raphe nucleus, rostral part B8 Median raphe nucleus B9 Pontis oralis nucleus
Sex differences in serotonergic activity in dorsal and median raphe nucleus. Physiology & Behavior, 80 (2-3), 203-210.
McDevitt and colleagues [57] found that 5-HT1B over-expression in the caudal dorsal raphe nucleus reduced expression of conditioned fear and depression-like behavior; they also found that systemic administration of the 5-HT1B agonist CP-94,253 reduced freezing.
Effect of xanthone from Kielmeyera coriacea stems on serotonergic neurons of the median raphe nucleus. Phytomedicine 17, 274-278.
Dorsal raphe nucleus serotonergic neurons innervate the rostral ventrolateral medulla in rat.
As mentioned above, the intergeniculate leaflet receives serotonergic innervation from the dorsal raphe nucleus (DNR), and the SCN receives serotonergic input from the median raphe nucleus [131].
We suspect in this particular patient that the SSRI caused release of serotonin in the Raphe Nucleus which has communication with the Substantia Nigra [6] leading to increased dopamine resulting in uncontrolled movements better known as "crack dancing" [6].
The researchers suspected that one part of the brain stem in particular, the dorsal raphe nucleus, might be crucial to behaviors that control effort.
Local administration of agonists in the dorsal raphe nucleus mainly produces a response similar to low-dose systemic administration, decreasing wakefulness and increasing REM sleep via disinhibition of mesopontine REM sleep-promoting neurons (Bjorvatn and Ursin, 1998).