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ranitidine/ra·ni·ti·dine/ (rah-nĭ´tĭ-dēn) a histamine H2 receptor antagonist, used as the hydrochloride salt to inhibit gastric acid secretion in the treatment of gastric and duodenal ulcer, gastroesophageal reflux disease, and conditions that cause gastric hypersecretion.
A histamine receptor antagonist, C13H22N4O3that inhibits gastric acid secretion and is used primarily to treat duodenal ulcers, gastric ulcers, and gastroesophageal reflux disease.
a histamine H2 receptor antagonist.
indications It is prescribed in the treatment of gastroesophageal reflux disease and gastric hypersecretory conditions.
contraindications Known sensitivity to this drug prohibits its use. The drug should be used in pregnancy only if clearly needed and with caution in those with severe hepatic or renal impairment.
adverse effects Among the most serious adverse effects are acquired hemolytic anemia, agranulocytosis, atrioventricular block, agitation, dizziness, headaches, rashes, gynecomastia, and loss of libido.
ranitidineZantac™ Therapeutics An H2-receptor antagonist used to treat peptic ulcer disease, gastric and duodenal ulcers, esophageal erosions, GERD, and conditions–eg, Zollinger-Ellison disease and systemic mastocytosis in which there is ↑ H2 activity due to blocking of the binding of histamine to H2 receptors, resulting in ↓ intracellular concentration of cAMP and acid secretion by gastric parietal cells Adverse reactions Diarrhea, headache, fatigue, myalgia, constipation, confusion, agranulocytosis, gynecomastia, impotence, allergic reactions, tachycardia, arrhythmias, interstitial nephritis, etc. See H2 blockers, Histamine receptor antagonists.
ranitidineAn H-2 (histamine-2) receptor antagonist drug used to reduce acid secretion in cases of peptic ulceration. A band name is Zantac. See also RANTITIDINE BISMUTH CITRATE.
a histamine H2-blocking agent used in the treatment of gastric ulceration and chronic hypertrophic gastritis.