randomised controlled trial

A trial in which participants are assigned by chance to receive either an experimental or control treatment. When randomisation is done properly, the effect of a treatment(s) can be studied in groups of people who are:
(1) the same at the outset, and
(2) treated the same way, except for the intervention(s) being studied. Any differences seen in the groups at the end can be attributed to the difference in treatment alone, and not to bias or chance.

References in periodicals archive ?

M2 EQUITYBITES-October 16, 2018-Reflexion Health's first randomised controlled trial in virtual physical therapy excels against traditional approach

Reflexion Health's first randomised controlled trial in virtual physical therapy excels against traditional approach

Global Banking News-October 16, 2018-Reflexion Health's first randomised controlled trial in virtual physical therapy excels against traditional approach

Reflexion Health's first randomised controlled trial in virtual physical therapy excels against traditional approach

M2 PHARMA-September 18, 2018-Actelion Pharmaceuticals reveals results of first randomised controlled trial in portopulmonary hypertension

Actelion Pharmaceuticals reveals results of first randomised controlled trial in portopulmonary hypertension

Six sessions of manual therapy increase knee flexion and improve activity in people with anterior knee pain: a randomised controlled trial. Aust J Physiother.

Combination Of Manual Therapy And Acupuncture For Pain Management Of Patients With Knee Osteoarthritis: Should a Combination of Manual Therapy and Acupuncture be the First Line of Therapy for Knee Osteoarthritis in Order to Prevent Arthroplastic Surgery? A Commentary on the Available Research

It was soon to become the standard control group of the randomised controlled trial. Instead of an inert sham given to individual patients, the placebo became the emblem for all the healing occurring in the disguised "no-treatment" arm of an RCT.

Revisiting the Randomized Controlled Trial

(2.) Sazawal S et al., Efficacy of chlorhexidine application to umbilical cord on neonatal mortality in Pemba, Tanzania: a community-based randomised controlled trial, Lancet Global Health, 2016, http://dx.doi.org/10.1016/S2214-109X(16)30223-6.

Umbilical cord cleansing may not be effective in reducing neonatal mortality in African settings

Randomised controlled trial of laparoscopic versus open mesh repair for inguinal hernia: outcome and cost.

COMPARISON OF LICHTENSTEIN TO TOTAL EXTRAPERITONEAL HERNIA REPAIR IN TERMS OF CLINICAL AND COST EFFECTIVENESS

In addition, the authors' conclusions regarding enteral feeding, although attractive on a physiological basis and perhaps correct, remain unproven in the absence of high-quality, level one, randomised controlled trial evidence.

Controversies in stress ulcer bleeding prophylaxis arise from differences in the quality of the evidence

Reducing SFA consumption is recommended to reduce CHD, but there is little strong randomised controlled trial (RCT) evidence of CHD events and few guidelines for specific SFA substitutes.

Replacing saturated with polyunsaturated fat to cut heart disease risk

Analyses from the extended follow-up of participants in a male circumcision randomised controlled trial conducted in Kisumu, Kenya, indicate that the protective effect of male circumcision was sustained, and possibly strengthened, for at least 42 months.

Key facts on male circumcision

Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet.

Does metoprolol prevent adverse outcomes for high-risk patients undergoing noncardiac surgery?

A new randomised controlled trial of the effectiveness of an intensive exercise program immediately after hospital has recently been published (Bulthuis 2007), and new studies examining the cost effectiveness of such programs should be done.

Short-term beneficial effects of physiotherapy exercise after knee arthroplasty for osteoarthritis