remains a mathematical exercise, of course, and in the real world, people's lives and behaviours are shaped by more than genetics.
Twenty-one RCTs were blinded (23,24,28,29,31,32,34,39,42,43,47,48,50,54,55,57,58,62,63,65,70) and in 16 studies the randomisation was adequate (25,29,31-34,42,47,48,55,57,62-64,73,74).
Similarly, bloodstream infections were reduced, albeit not significantly, in studies with adequate randomisation, unblinded and with low quality, and in studies using parenteral and enteral anti-microbials.
The deal will see ClinIntel's offerings combined into the ClinPhone RTSM range and is intended to make patient randomisation
and clinical supply chain solutions more efficient.
According to Professor Hypponen, "Mendelian randomisation
helps to determine cause and effect because by using genetic data we can better avoid confounding, reverse causation, and bias.
Upon entry into the study, patients took part in a screening period of up to two weeks, a randomisation
visit (visit 2) followed by a treatment period of 26 weeks where patients attended 3 on-treatment clinic visits.
According to Medtronic the primary endpoints of the study are the change in blood pressure from baseline to six months following randomisation
and the incidence of major adverse events one month following randomisation
and renal artery stenosis to six months.
Cenduit, a company that helps pharmaceutical and biotech companies to control the processes of patient enrolment, patient randomisation
, and drug supply, has introduced a new study simulation and forecasting service for clinical trials, it was reported yesterday.
Cenduit, a patient randomisation
and clinical supplies management services provider, is expanding its headquarters in Durham, North Carolina, United States and its office in Basel, Switzerland, it was reported on Friday.
M2 PHARMA-December 9, 2011-Boehringer Ingelheim completes randomisation
in Phase III hepatitis C study(C)2011 M2 COMMUNICATIONS
M2 EQUITYBITES-10 August 2010-Amarin announces completion of patient enrolment and randomisation
in Pivotal Phase 3 MARINE Clinical Trial for AMR101(C)2010 M2 COMMUNICATIONS http://www.m2.com