Exposure to ionising radiation may result in radioresistant
subclones being selected and giving rise to tumour relapse.
Clear indications for surgery include unknown primary where computed tomography-guided biopsy is not possible or has not been successful, progressive neurologic dysfunction despite radiotherapy, steroids, or chemotherapy, radioresistant
tumors or tumors with poor radioresponsivity, tumors that have progressed or recurred after radiation, instability due to bony destruction, and neural element compression by displaced bone fragments.
Chordomas have been considered radioresistant
Although chordomas are thought to be radioresistant
, several studies attest to the efficacy of adjunctive radiation therapy, particularly with fractionated proton beam therapy.
unvaccinated patients suggest that recurrent tumors bear more chemoresistant and radioresistant
cancer stem cells; and ICT-107 vaccinated patients have a decreased proportion of cancer stem cells from immunological targeting.
27) Photoreceptor differentiation is more common in eyes enucleated after radiotherapy or chemotherapy because the well-differentiated part of the tumor is relatively radioresistant
Radiation is no longer a treatment option for those whose cancer reoccurs, however, since the tumors have already been shown to be radioresistant
and any re-treatment would put a patient at risk of serious complications.
1 established the diagnosis of an autonomous nodule rather than Graves disease, and this information was used to select a relatively high therapeutic dose of radioiodine because toxic nodular goiters are more radioresistant
than Graves disease thyroid glands (31).
This approach has the potential to solve one of the biggest problems in treating radioresistant
tumors with radiotherapy: how to increase the dose inside the tumor without harming the surrounding healthy tissue," said Prof.
7) Because neurilemmomas are extremely radioresistant
, radiotherapy has no role in their management.
Salvage surgery plus androgen deprivation for radioresistant
PARIS -- Nanobiotix, an emerging nanomedicine company, announced today that preclinical follow-up data regarding long-term toxicity evaluation suggests that its patented NBTXR3 nanoparticles are designed to be a safe and effective treatment for radiosensitive and radioresistant