The effort to develop radioprotectant
agents has been initiated decades ago in order to protect human cells from radiation damage whereby synthetic and natural compounds have been studied (Ahmad et al., 2013).
Mehrali, "Lycopene as a carotenoid provides radioprotectant
and antioxidant effects by quenching radiation-induced free radical singlet oxygen: an overview," Cell Journal, vol.
Yesterday it was revealed that the National Cancer Institute has awarded a grant to Minneapolis-based Humanetics to assess their proprietary radioprotectant
compound, BIO 300, as a potential treatment for erectile dysfunction following prostate cancer radiotherapy.
Calcitrol, the active form of vitamin D3, is a terrific radioprotectant
, even against low-level background radiation.
(60), (61) BBI survives processing in commercial soybean products (e.g., soy milk, soybean concentrate, and soy protein isolates), making it a highly accessible radioprotectant
. (62), (63)
They have been described also as radioprotectant
, antioxidant and anticancer.
Prophylaxis of kanamycin-induced ototoxicity by a radioprotectant
. Hear Res 1981;4(1):79-87.
The Clearant Process, licensed to CryoLife from Clearant, Inc., is a patented technology based on gamma irradiation and a radioprotectant
that is designed to inactivate pathogens, including microorganisms while maintaining tissue integrity.
Cancellous bone dowels, provided by AlloSource, were randomly divided into a non-irradiated control group (n=24), a 50kGy optimized irradiation group pre-treated with a radioprotectant
solution (n=24), as well as a third group irradiated by AlloSource (n=10) to a targeted dose of 18kGy using their standard practices.
AFRRI has screened thousands of compounds in an effort to find a radioprotectant
suitable for widespread use.
The sulphydryl compound amifostine, which is the only radioprotectant
approved to be used in humans by FDA, has shown effective radioprotective ability .
(36), (37) BBI survives processing in commercial soybean products (e.g., soymilk, soybean concentrate, and soy protein isolates), making it a highly accessible radioprotectant
. (38), (39)