Calcitrol, the active form of vitamin D3, is a terrific radioprotectant
, even against low-level background radiation.
soy milk, soybean concentrate, and soy protein isolates), making it a highly accessible radioprotectant
They have been described also as radioprotectant
, antioxidant and anticancer.
Prophylaxis of kanamycin-induced ototoxicity by a radioprotectant
is a patented technology based on gamma irradiation and a radioprotectant
that is designed to inactivate pathogens, including microorganisms while maintaining tissue integrity.
Cancellous bone dowels, provided by AlloSource, were randomly divided into a non-irradiated control group (n=24), a 50kGy optimized irradiation group pre-treated with a radioprotectant
solution (n=24), as well as a third group irradiated by AlloSource (n=10) to a targeted dose of 18kGy using their standard practices.
AFRRI has screened thousands of compounds in an effort to find a radioprotectant
suitable for widespread use.
In addition, Hollis-Eden recently entered into a Cooperative Research and Development Agreement (CRADA) with the United States Department of Defense to develop HE2100 as a radioprotectant
(a drug that may potentially be used to protect a person from radiation injury due to a nuclear accident or event).
Na), Onconova is also developing Ex-RAD(TM), an injectable and oral radioprotectant
, and inhibitors of Plk2, ALK, CDK, JAK, and Bcr-abl pathways and a novel immunoconjugate platform for arming therapeutic antibodies.
announces that its lead product, Rx100, a potent radioprotectant
as well as radiomitigator, protects against lethal, whole-body radiation when administered before, during, or up to 72 hours after exposure.
Further, Onconova has a promising portfolio of earlier stage clinical candidates including Ex-RAD([R]), which has demonstrated proof-of-principle as a novel radioprotectant
, and ON 013105 which is in clinical development for lymphoma.
Rx100 is unique as a radioprotectant
/ radiomitigator in that it can be administered orally or by subcutaneous injection and it possesses a variety of favorable product characteristics that make it an ideal agent for use as a radiation countermeasure.