radial glial cell


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radial glial cell

A structural macroglial cell that is a key component of the developing nervous system. Radial glial cells first appear in the neural tube, where their cell bodies are suspended between two thin cell processes; the apical process attaches to the inner (ventricular) surface of the neural tube, and the basal process attaches to the outer (pial) surface. Early in development, neuroblasts migrate radially along the scaffolding formed by the radial glial cell processes, and growing axons may follow the scaffolding longitudinally. Later, many radial glial cells retract their processes and differentiate into astrocytes.
See also: cell
References in periodicals archive ?
Caption: FIGURE 2: CD60b expression in radial glial cells in the newborn brain.
"To the best of our knowledge this is the first example of any signaling pathway affecting the proliferation of radial glial cells whose activity has changed during mammalian evolution," Oldham said.
In this report, we propose a novel therapeutic approach using stem cell-derived radial glial cells in combination with a magnetically aligned fibrin scaffold for targeted axonal regeneration.
2005211847); "Production of Radial Glial Cells" was issued by the Canadian Intellectual Property Office (No.
The brain cytochrome P450 aromatase (Aro-B) in zebrafish is expressed in radial glial cells and is strongly stimulated by estrogens ([E.sub.2]); thus, it can be used in vivo as a biomarker of xenoestrogen effects on the central nervous system.
Radial glial cells of the retina (commonly referred to as Mailer cells) are believed to play a crucial role in maintaining the normal functional capabilities of this most peripheral extension of the central nervous system.