racemization


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racemization

 [ra″sĕ-mĭ-za´shun]
the transformation of one-half of the molecules of an optically active compound into molecules that possess exactly the opposite (mirror-image) configuration, with complete loss of rotatory power because of the statistical balance between equal numbers of dextrorotatory and levorotatory molecules.

ra·ce·mi·za·tion

(rā'sē-mi-zā'shŭn, rās-mi-),
Partial conversion of one enantiomorph into another (as an l-amino acid to the corresponding d-amino acid) so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.

racemization

/ra·ce·mi·za·tion/ (ra″sĕ-mĭ-za´shun) the transformation of one half of the molecules of an optically active compound into molecules having exactly the opposite configuration, with complete loss of rotatory power because of the statistical balance between the equal numbers of dextro- and levorotatory molecules.

ra·ce·mi·za·tion

(rā'sĕ-mī-zā'shŭn)
Partial conversion of one enantiomorph into another (as an l-amino acid to the corresponding d-amino acid) so that the specific optic rotation is decreased, or even reduced to zero, in the resulting mixture.

racemization

the transformation of one-half of the molecules of an optically active compound into molecules that possess exactly the opposite (mirror-image) configuration, with complete loss of rotatory power because of the statistical balance between equal numbers of dextrorotatory and levorotatory molecules.
References in periodicals archive ?
One disadvantage of the AAR dating method is that the chemical racemization process is sensitive to environmental factors, especially to temperature.
PLP is the active coenzyme product of the vitamin B6 pathway and is essential in many biochemical reactions, including decarboxylation, transamination, deamination, racemization and trans-sulfuration reactions associated primarily with amino acid synthesis [12].
The details of Marr's sequence need not concern us, except to note that it has recently been reappraised by Steve Boreham and who, through amino acid racemization analysis of a Pupilla muscorum shell, tentatively assigned its upper gravels to the early part of the 'Wolstonian' interval (MIS 9/10; c.
In 2007, researchers at CEM showed in a major publication that precise temperature control limits major side reactions such as racemization and aspartimide formation(2).
Acid hydrolysis of foods also causes some racemization of amino acids [31], as does roasting of proteins or protein containing food above 200[degrees]C [32].
12] Garnero P, Cloos P, Sornay-Rendu E, Qvist P, Delmas PD Type I collagen racemization and isomerization and the risk of fracture in postmenopausal women: the OFELY prospective study.
They include oxidation, racemization, isomerization, deamidation, nitration, carbonylation, carbamylation, and glycation (or glycoxidation) (1).
This textbook for graduate students embraces asymmetric synthesis, interconversion of chiral compounds, and analytical methods for the study of racemization and diastereomerization reactions, and discusses topologically chiral assembles and molecular propellers, switches, and motors in the context of dynamic stereochemistry.
The L-Asp/D-Asp acid system was chosen motivated by the importance of LAsp acid in human metabolism, such as removing toxins from the bloodstream and the use of L-Asp racemization ratios in human serum for age estimation [46].
Aluminium induced racemization of Aspartate and Glutamate in the hippocampal region of rabbit brain: relevance to Alzheimer's disease.
Moreover, during the oxidative work-up procedure in basic conditions the lactone ring may open and, together with the following relactonization, there is a risk of racemization of (1S, 5R, 6R)4a (the enantiopurity of the other diastereomer (1S, 5R, 6S)-4a is not affected).
Thaler's] study is significant because it marks the first time that racemization has been looked on as a sign of life on other planets," emphasizes Andreas Bommarius, professor of biomolecular engineering.