racemase


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racemase

 [ra´sĕ-mās]
an enzyme that catalyzes the racemization of an optically active substance, such as l-lactic acid.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ra·ce·mase

(rā'sē-māz),
An enzyme capable of catalyzing racemization, that is, inversions of asymmetric groups; when more than one center of asymmetry is present, "epimerase" is used (for example, hydroxyproline, methylmalonyl-CoA).
Farlex Partner Medical Dictionary © Farlex 2012

ra·ce·mase

(rā'sĕ-mās)
An enzyme capable of catalyzing racemization, i.e., inversions of asymmetric groups; when more than one center of asymmetry is present, "epimerase" is used.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Value of CDX2, uillin, and alpha-methylacyl coenzyme A racemase immunostains in the distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma.
In enzymology, alpha-methylacyl-CoA racemase (AMACR) is an enzyme that catalyses chemical reactions.
Abbreviations: PSAT, phosphoserine aminotransferase; PSP, phosphoserine phosphatase; SR, serine racemase.
D-serine is produced from L-serine by the enzyme serine racemase which can be a cause of the decreased serum levels of L-serine as was observed in our study.
Diagnostic utility of alpha-methylacyl CoA racemase (P504S) & HMWCK in morphologically difficult prostate cancer.
The gene alr encodes for alanine racemase and is involved in the peptidoglycan synthesis, yet the function of this enzyme in Mycoplasma species is not clear.
Supportive findings include the expression of proximal convoluted tubule markers (CD10 and alpha-methylacyl-CoA racemase; AMACR), distal nephron proteins (parvalbumin, high-molecular-weight CK, and CD19) [1, 6], and the detection of intercalated cells and cells similar to those in the proximal tubule using electron microscopy [1, 7, 8].
Tomaszewski, "Role of carbonic anhydrase IX, [alpha]-methylacyl coenzyme a racemase, cytokeratin 7, and galectin-3 in the evaluation of renal neoplasms: a tissue microarray immunohistochemical study," Annals of Diagnostic Pathology, vol.
Immunohistochemistry is helpful in differentiating these entities as CA-IX and CD10 are most frequently expressed in CCRCC than Mullerian CCC, whereas CK7, Napsin-A, and methylacyl-coenzyme-A racemase (AMACR) show a reverse pattern of expression [3].
Specifically, neuronal activity facilitated [H.sub.2]S production and sulfhydrated serine racemase (SR) formation, and use of an [H.sub.2]S donor enhanced hippocampal D-serine availability, expedited hippocampal LTP via a D-serine-dependent pathway, and slowed age-related LTP impairment [41].
D-serine is synthetized by isomerization of L-serine, in a reaction catalyzed by the enzyme serine racemase [24, 25], which, in addition to synthesize D-serine, also catalyzes the [alpha],[beta]-elimination of water from L-serine or D-serine to produce pyruvate and ammonia [26] (Figure 1).