An agonist at glutamate receptors of the amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) type. The anion formed when quisqualic acid is dissolved in water. See: quisqualic acid.
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80, 81) At least three receptor types are generally accepted as being responsible for glutamate excitotoxicity--those selectively activated by NMDA, quisqualate, and kainate.
81) KYNA is a tryptophan metabolite that has selective activity against NMDA, quisqualate, and kainate receptors in the central nervous system.
Quisqualate was an even more potent agonist than glutamate, while L-aspartate was as potent as glutamate (Hashemzadeh-Gargari and Freschi, 1992).
initiation of swimming activity in the medicinal leech by glutamate, quisqualate, and kainate.