quinolones


Also found in: Dictionary.
Related to quinolones: ciprofloxacin, Aminoglycosides

quin·o·lones

(kwin'ō-lōnz),
A class of synthetic broad-spectrum antibacterial agents with bactericidal action (for example, ciprofloxacin).

quin·o·lones

(kwin'ō-lōnz)
A group of antimicrobial agents (e.g., norfloxacin, ciprofloxacin, levofloxacin) that block bacterial DNA synthesis.

quinolones

A group of synthetic antibiotic drugs that includes nalidixic acid, oxfloxacin and enoxacin. These drugs act by inactivating an enzyme, DNA gyrase, necessary for replication of the organisms.

quinolones 

A class of broad-spectrum antibacterial drugs of which the main ophthalmic agents are ciprofloxacin and ofloxacin. They are used topically in 0.3% solution. They are effective against the majority of gram-negative pathogens, including Haemophilus, Neisseria gonorrhoeae, Chlamydia trachomatis, Pseudomonas aeruginosa (especially ciprofloxacin), staphylococci and streptococci. They are used in the treatment of conjunctivitis, blepharitis, keratoconjunctivitis and corneal ulcers. See antibiotic.

quin·o·lones

(kwin'ō-lōnz)
Synthetic broad-spectrum antibacterial agents with bactericidal action.

quinolones

drugs that have good effect against all species of chicken coccidia but have a bad tendency to generate resistant strains and are now rarely used for that purpose; newer derivatives are used as antibacterials.
References in periodicals archive ?
Correlation of in vitro susceptibilities to quinolones of naturally occurring quinolone-resistant Neisseria gonorrhoeae strains isolated with changes in gyrA and parC in China.
The study's authors said a few individuals traveling outside the region may have been exposed to quinolones and on return transmitted resistant organisms to their neighbors.
A 1997 database review compiled reports of skeletally immature patients ranging in age from 4 days to 26 years who were exposed to quinolones.
Two other quinolones, norfloxacin and lomefloxacin, are used primarily to treat urinary tract and prostate infections, and ofloxacin is another that is manufactured in a topical form for ear and eye disease.
One would hope that their further characterization and source search would include ongoing investigation of resistance to quinolones.
Since 1995, when the Food and Drug Administration approved quinolones for use in poultry, the rates of resistance have gone up dramatically.
Pullorum isolates collected from infected chickens in Brazil to different classes of antimicrobial drugs, including [beta]-lactams and quinolones, used currently or in the past in animal production.
Objective: To determine the clonal relationship of ESBL-producing and quinolone resistant E.
2) Quinolones and fluoroquinolones are broad spectrum antibacterial agents commonly used in both clinical and veterinary medicine.
But prescriptions for quinolones grew by 10%, and prescriptions for cephalosporins grew by 3%, both of which were statistically significant increases (P less than .
McGregor and her associates reported, but prescriptions for quinolones grew by 10% and prescriptions for cephalosporins grew by 3%, which were statistically significant increases (P less than .