quinolones


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Related to quinolones: ciprofloxacin, Aminoglycosides

quin·o·lones

(kwin'ō-lōnz),
A class of synthetic broad-spectrum antibacterial agents with bactericidal action (for example, ciprofloxacin).

quin·o·lones

(kwin'ō-lōnz)
A group of antimicrobial agents (e.g., norfloxacin, ciprofloxacin, levofloxacin) that block bacterial DNA synthesis.

quinolones

A group of synthetic antibiotic drugs that includes nalidixic acid, oxfloxacin and enoxacin. These drugs act by inactivating an enzyme, DNA gyrase, necessary for replication of the organisms.

quinolones 

A class of broad-spectrum antibacterial drugs of which the main ophthalmic agents are ciprofloxacin and ofloxacin. They are used topically in 0.3% solution. They are effective against the majority of gram-negative pathogens, including Haemophilus, Neisseria gonorrhoeae, Chlamydia trachomatis, Pseudomonas aeruginosa (especially ciprofloxacin), staphylococci and streptococci. They are used in the treatment of conjunctivitis, blepharitis, keratoconjunctivitis and corneal ulcers. See antibiotic.

quin·o·lones

(kwin'ō-lōnz)
Synthetic broad-spectrum antibacterial agents with bactericidal action.
References in periodicals archive ?
According to 62%GP's effective order of preference of drugs was quinolones, 3rd generation cephalosporin and ampicillin while 3rd generation cephalosporins, quinolones, azithromycin, ampicillin and chloramphenicol was effective order answered by 32% GP's.
Conclusion: Major deficiencies were treatment of severe pneumonia in community, inappropriate use of quinolones and poor knowledge of recent guidelines.
Resistant strains to trimethoprim-sulfamethoxazole and quinolones were stored at -70 qC.
Writing in the journal, the team concluded: "Use of macrolides (excluding erythromycin), quinolones, tetracyclines, sulphonamides and metronidazole during early pregnancy was associated with an increased risk of spontaneous abortion.
The first quinolone (quinoJ[ine] + -one [compound related to ketone]), nalidixic acid, was isolated as a byproduct of chloroquine (see "quinine," https://wwwnc.
This shows the mixed pattern but increase in resistance to quinolones over a decade.
The evolving antimicrobial resistance scenario is reminiscent of the quinolone experience, he added.
Thirteen patients made full recovery, five of which were treated with a quinolone and macrolide, with the others having either a quinolone or macrolide as part of their treatment.
The aim of this study was to determine the presence of several VFs and the levels and molecular mechanisms of resistance to quinolones and macrolides in a series of Campylobacter spp.