A class of alkaloids based on the quinolizidine (norlupinane) structure.
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The lycopodium alkaloid huperzine A [9] related to the quinolizidines, is a potent, yet reversible, inhibitor of AChE and is used in China for treating patients with myasthenia gravis and AD.
These were investigated further for the occurrence of quinolizidine alkaloids using GC-MS with a nitrogren-specific detector (Greinwald & Meurer-Grimes, unpubl.).