quellung reaction


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quel·lung re·ac·tion

2. if pneumococcal organisms, India ink, and specific antisera are mixed, the antibodies present in the sera will bind to the polysaccharide antigens of the pneumococcal capsule and the capsule will appear more opaque and swollen. This test will identify the organism as being pneumococcal as well as the specific capsular types. Synonym(s): capsular precipitation reaction
[Ger. Quellung, swelling]

quellung reaction

[kwel′ung]
Etymology: Ger, Quellung, swelling; L, re, again, agere, to act
the swelling of the capsule of a bacterium, seen in the laboratory when the organism is exposed to specific antisera. This phenomenon is used to identify the genera, species, or subspecies of the bacteria causing a disease, including Haemophilus influenzae, Neisseria meningitidis, and many kinds of streptococci.

quel·lung re·ac·tion

(kvel'lung rē-ak'shŭn)
1. Synonym(s): Neufeld capsular swelling.
2. If pneumococcal organisms, India ink, and specific antisera are mixed, the antibodies present in the sera will bind to the polysaccharide antigens of the pneumococcal capsule and the capsule will appear more opaque and swollen.
[Ger. Quellung, swelling]

Neufeld,

Ferdinand, German bacteriologist, 1869-1945.
Neufeld capsular swelling - increase in opacity and visibility of the capsule of capsulated organisms exposed to specific agglutinating anticapsular antibodies. Synonym(s): Neufeld quellung reaction; Neufeld reaction; quellung phenomenon; quellung reaction; quellung test
Neufeld quelling reaction - Synonym(s): Neufeld capsular swelling
Neufeld reaction - Synonym(s): Neufeld capsular swelling
References in periodicals archive ?
Serotypes were determined by Quellung reaction or PCR testing or predicted based on complete multilocus sequence typing, as described in the text.
All pneumococcal isolates were serotyped according to standard methods by using the Quellung reaction (15-17).
Serotyping was conducted by using the quellung reaction with reagents from Statens Serum Institut (Copenhagen, Denmark) (18).
Pneumococcal serotypes were determined at the Centers for Disease Control and Prevention by the latex agglutination test and confirmed with Quellung reaction.
All isolates were serotyped by the quellung reaction (6) with sera of various levels of reactivity from the Statens Seruminstitut (Copenhagen, Denmark).