quellung reaction


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quel·lung re·ac·tion

2. if pneumococcal organisms, India ink, and specific antisera are mixed, the antibodies present in the sera will bind to the polysaccharide antigens of the pneumococcal capsule and the capsule will appear more opaque and swollen. This test will identify the organism as being pneumococcal as well as the specific capsular types. Synonym(s): capsular precipitation reaction
[Ger. Quellung, swelling]

quel·lung re·ac·tion

(kvel'lung rē-ak'shŭn)
1. Synonym(s): Neufeld capsular swelling.
2. If pneumococcal organisms, India ink, and specific antisera are mixed, the antibodies present in the sera will bind to the polysaccharide antigens of the pneumococcal capsule and the capsule will appear more opaque and swollen.
[Ger. Quellung, swelling]

Neufeld,

Ferdinand, German bacteriologist, 1869-1945.
Neufeld capsular swelling - increase in opacity and visibility of the capsule of capsulated organisms exposed to specific agglutinating anticapsular antibodies. Synonym(s): Neufeld quellung reaction; Neufeld reaction; quellung phenomenon; quellung reaction; quellung test
Neufeld quelling reaction - Synonym(s): Neufeld capsular swelling
Neufeld reaction - Synonym(s): Neufeld capsular swelling
References in periodicals archive ?
However, 10 strains were not distinguished by the standard method (quellung reaction) because they reacted with both factors, 6b and 6c.
Serotypes were determined by Quellung reaction or PCR testing or predicted based on complete multilocus sequence typing, as described in the text.
Pneumococcal serotypes were determined at the Centers for Disease Control and Prevention by the latex agglutination test and confirmed with Quellung reaction. The presence of mef and/or ermB was determined by using a duplex polymerase chain reaction (PCR) (7), and mefA was differentiated from mefE by PCR-restriction fragment length polymorphisms (8).
All isolates were serotyped by the quellung reaction (6) with sera of various levels of reactivity from the Statens Seruminstitut (Copenhagen, Denmark).
Serotyping was performed by the Quellung reaction (Quellung antisera, Staten Seruminstitut, Copenhagen).
Pneumococcal serogrouping was performed with the Quellung reaction with a standard technique (5) and a diagnostic kit from Statens Serum Institut (SSI), Copenhagen, Denmark.