quellung reaction

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Related to quellung: quellung test

quel·lung re·ac·tion

2. if pneumococcal organisms, India ink, and specific antisera are mixed, the antibodies present in the sera will bind to the polysaccharide antigens of the pneumococcal capsule and the capsule will appear more opaque and swollen. This test will identify the organism as being pneumococcal as well as the specific capsular types. Synonym(s): capsular precipitation reaction
[Ger. Quellung, swelling]

quellung reaction

[kwel′ung]
Etymology: Ger, Quellung, swelling; L, re, again, agere, to act
the swelling of the capsule of a bacterium, seen in the laboratory when the organism is exposed to specific antisera. This phenomenon is used to identify the genera, species, or subspecies of the bacteria causing a disease, including Haemophilus influenzae, Neisseria meningitidis, and many kinds of streptococci.

quel·lung re·ac·tion

(kvel'lung rē-ak'shŭn)
1. Synonym(s): Neufeld capsular swelling.
2. If pneumococcal organisms, India ink, and specific antisera are mixed, the antibodies present in the sera will bind to the polysaccharide antigens of the pneumococcal capsule and the capsule will appear more opaque and swollen.
[Ger. Quellung, swelling]

Neufeld,

Ferdinand, German bacteriologist, 1869-1945.
Neufeld capsular swelling - increase in opacity and visibility of the capsule of capsulated organisms exposed to specific agglutinating anticapsular antibodies. Synonym(s): Neufeld quellung reaction; Neufeld reaction; quellung phenomenon; quellung reaction; quellung test
Neufeld quelling reaction - Synonym(s): Neufeld capsular swelling
Neufeld reaction - Synonym(s): Neufeld capsular swelling
References in periodicals archive ?
For each strain transferred to our laboratory, we promptly identified capsular type by quellung reaction, and resistance genotype was determined by real-time PCR.
pneumoniae isolates were serotyped by using type-specific antisera and observation of the Quellung reaction at the Streptococcus Laboratory (Centers for Disease Control and Prevention, Atlanta, GA, USA).
These isolates, used as controls, had been serotyped by quellung reaction at the Instituto de Salud Carlos III, Majadahonda-Madrid, Spain.
Results were confirmed by the Quellung reaction with newly available antiserum to identify 6C serotype (Statens Serum Institute, Copenhagen, Denmark).
Serotype 6C was identified in 2007 on the basis of its distinct binding patterns with 2 monoclonal antibodies; serotype 6C had previously been typed as 6A according to the standard quellung reaction.
Serotyping was performed by using the quellung reaction with antiserum for serogroup 6, factor 6b, and factor 6c (Statens Serum Institute, Copenhagen, Denmark).
Isolates were serotyped by using the Quellung reaction (9).
pneumoniae by standard methods, and serotypes were determined by the Quellung reaction.
Conventional serotyping using the Quellung method was performed where possible; culture-negative or incompletely genotyped PFs were serotyped by using a real-time PCR that targets different capsular locus genes (13).
All isolates were serotyped by the Quellung reaction using antiserum (Statens Serum Institute, Copenhagen, Denmark).
Isolates were serotyped by the Quellung reaction (Alaska, northern Canada, Greenland, Norway, and northern Sweden), counter-immunoelectrophoresis (Finland), or coagglutination (Iceland).