quellung reaction

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Related to quellung: quellung test

quel·lung re·ac·tion

2. if pneumococcal organisms, India ink, and specific antisera are mixed, the antibodies present in the sera will bind to the polysaccharide antigens of the pneumococcal capsule and the capsule will appear more opaque and swollen. This test will identify the organism as being pneumococcal as well as the specific capsular types. Synonym(s): capsular precipitation reaction
[Ger. Quellung, swelling]

quel·lung re·ac·tion

(kvel'lung rē-ak'shŭn)
1. Synonym(s): Neufeld capsular swelling.
2. If pneumococcal organisms, India ink, and specific antisera are mixed, the antibodies present in the sera will bind to the polysaccharide antigens of the pneumococcal capsule and the capsule will appear more opaque and swollen.
[Ger. Quellung, swelling]

Neufeld,

Ferdinand, German bacteriologist, 1869-1945.
Neufeld capsular swelling - increase in opacity and visibility of the capsule of capsulated organisms exposed to specific agglutinating anticapsular antibodies. Synonym(s): Neufeld quellung reaction; Neufeld reaction; quellung phenomenon; quellung reaction; quellung test
Neufeld quelling reaction - Synonym(s): Neufeld capsular swelling
Neufeld reaction - Synonym(s): Neufeld capsular swelling
References in periodicals archive ?
Serologic comparison of 35B/ST156 lineage strains with CDC Quellung reagents for resolution of serogroup 35B invasive serotype pneumococci including an expanding serotype switch lineage, United States, 2015-2016 * Quellung factor Strain 35b 29b 35c 42a 35a cps35B ([dagger]) - + + - + cps35B (wciG deletion) - + + - - ([double dagger]) * CDC, Centers for Disease Control and Prevention; ST, sequence type; -, negative; +, positive.
Identification of capsular type by the quellung reaction and resistance genotyping by real-time PCR was performed within 1 day of sample collection for each strain.
Serotypes of all isolates were determined by the capsular quellung reaction using antiserum purchased from the Statens Serum Institute (Copenhagen, Denmark).
Serogrouping and serotyping were performed by the quellung reaction using antiserum provided by Statens Serum Institute (Copenhagen, Denmark) (8).
The capsular serotype of all isolates was determined by using the Quellung reaction with antisera from the Statens Serum Institut (Copenhagen, Denmark).
At the NRLBM, co-agglutination was used to type the pneumococcal isolates and the capsular swelling method (Quellung reaction), using antisera (Statens Serum Institute, Copenhagen, Denmark), including serotype 6C, was used for serotyping.
All pneumococcal isolates that exhibited a positive quellung reaction when commercial type-specific antiserum (Statens Serum Institute, Copenhagen, Denmark) was used were assigned a serotype (10).
pneumoniae isolates were serotyped by using type-specific antisera and observation of the Quellung reaction at the Streptococcus Laboratory (Centers for Disease Control and Prevention, Atlanta, GA, USA).
These isolates, used as controls, had been serotyped by quellung reaction at the Instituto de Salud Carlos III, Majadahonda-Madrid, Spain.
pneumoniae, then 1 pneumococcal colony per plate was subcultured and serotyped by the capsular swelling method (Quellung reaction).
Serotype 6C was identified in 2007 on the basis of its distinct binding patterns with 2 monoclonal antibodies; serotype 6C had previously been typed as 6A according to the standard quellung reaction.
Isolates were serotyped by using the Quellung reaction (9).