quasispecies

quasispecies

 [quah″zĭ-spe´sēz]
a swarm of virus with similar genetic structure sharing a host with other quasispecies of different genetic makeup; usually all quasispecies in one host are descended from a single ancestor strain.
References in periodicals archive ?
Selection of resistant mutants with current STAT-C is not surprising as HCV bears all the characteristics required for the generation of mutant viruses, including rapid turnover (1012 virions a day) due to high replication levels and a quasispecies distribution of viral populations.
Learning from HIV: how will drug resistance influence treatment strategies against hepatitis C?
Hepatitis C virus (HCV) circulate as a population of different but closely related genomes: quasispecies nature of HCV genome distribution.
High-speed detection of blood-borne Hepatitis C virus RNA by single-tube real-time fluorescence reverse transcription-PCR with the LightCycler
Further studies evaluating viral fitness of West Nile virus quasispecies in terms of population-dependent host-virus interactions, are warranted.
Virulence and evolution of West Nile virus, Australia, 1960-2012
Quasispecies analysis was performed on the specimens that shared identical NS5b sequences (3).
Transmission of hepatitis C virus through transplanted organs and tissue--Kentucky and Massachusetts, 2011
In addition, HCV has a high rate of spontaneous mutation, producing discrete "quasispecies" that vary from one individual to the next (195).
Diagnosis and monitoring of hepatic injury. I. Performance characteristics of laboratory tests
Middle East respiratory syndrome coronavirus quasispecies that include homologues of human isolates revealed through wholegenome analysis and virus cultured from dromedary camels in Saudi Arabia.
Infection, replication, and transmission of middle east respiratory syndrome coronavirus in alpacas
HCV core protein is a structural protein and its sequence is highly conserved among all HCV genotypes and quasispecies. (9) Detection of HCV core antigens (HCVcAg) for the diagnosis of HCV infection, particularly in the pre-seroconversion window period (PSWP), can be accomplished by several assays that are available for research or commercial purposes, using serum, plasma or whole blood samples.
Hepatitis C virus core antigen assay: Can we think beyond convention in resource limited settings?
Rapid quantitation of neuraminidase inhibitor drug resistance in influenza virus quasispecies. Antivir Ther 2008;13:809-20.
Update: drug susceptibility of swine-origin influenza A (H1N1) viruses, April 2009
In chronic hepatitis, an acute increase in aminotransferases mimicking acute hepatic injury can occur with clearance of HBV e antigen (HBeAg) (45) or with emergence of quasispecies of HCV (46).
Diagnosis and monitoring of hepatic injury. II. Recommendations for use of laboratory tests in screening, diagnosis, and monitoring
No similar mutations occurred in parallel transmission chains leading up to patients 35, 168, and 163, suggesting that quasispecies sampling during transmission events has been stochastic rather than selective.
Microevolution of outbreak-associated Middle East respiratory syndrome coronavirus, South Korea, 2015
Dynamics of virus quasispecies during serial passages in heterologous hosts.
Desmodus rotundus and Artibeus spp. bats might present distinct rabies virus lineages
This inadequacy may be further strengthened by the nonrandom distribution of HCV quasispecies in plasma and peripheral blood mononuclear cell subsets (9).
Evaluation of a minipool reverse transcription-PCR screening method for the detection of hepatitis C virus infection in hemodialysis patients
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