Hippocrates was the first to clearly describe the different types of malaria depending upon the periodicity of the fever--tertian and quartan fever
Nature of Man, which best describes humor theory, proposes a new humor in place of water: black bile, causing diseases of the kidneys, spleen, liver, quartan fever
, headaches, and epilepsy.
5) A self-avowed melancholic born under the sign of Saturn,(6) Ficino attributes quartan fever
to a poor combustion of melancholy humor: "If black bile .
The item on Atticus' estate in Epirus (66-78) looks like a meritorious piece of research (I cannot speak with knowledge of the topography), including the interesting suggestion that Atticus' quartan fever
and the ill health of his wife and daughter derived from this malarial source.
I gave him two drams of opium, but he suffered from quartan fever
, and its crisis halted the effect of the drug.
This may well have enhanced transmission rates, for Thomas Sydenham described an epidemic of tertian and some quartan fevers
in 1661, which "was doing frightful mischief' by August.