" She called on Government to fund the treatment as quickly as possible, saying the price cap of PS300,000 per quality adjusted life year
failed to illustrate the power of the drug, which experts agree could give children who would otherwise die as teenagers significantly more than the 30 years of extra quality life which is the maximum NHS England takes into account when considering a treatment.
A commonly used measure of utility is quality adjusted life year
(QALY), which is calculated by estimating life years gained from a treatment or therapy and then weighting each year to reflect the quality of one's life during the year.
But a preliminary appraisal by the New Medicines Group issued to AWMSG says the case for cost-effectiveness for the drug "has not been proven" and estimates the cost to be more than PS500,000 per quality adjusted life year
- a measurement which looks at both the quality and the quantity of life added by a drug.
Researchers used the Quality Adjusted Life Year
(QALY) scale to measure benefit to patients in comparison to the direct and indirect costs of the surgical procedures over a two-year period after surgery.
As to establishing the value of a drug under the proposed scheme, the OFT advocates the Quality Adjusted Life Year
('QALY') measure used by the National Institute of Clinical Excellence ('NICE').
Assuming a 1% prevalence of HIV infection (100/10,000), and factoring in the benefits of reduced transmission, these studies suggest that routine screening would cost about $15,000 per quality adjusted life year
. Even if the prevalence were as low as 5/10,000, the cost per quality adjusted life year
would still be under $50,000.
'Set against the Quality Adjusted Life Year
scale, which measures 'life gains', it works out about pounds 19,000 but compared to the cost of prescribing antibiotics for meningitis, it's still an expensive option.
From the payer standpoint, DIMM clinic patients achieved greater Quality Adjusted Life Years
with lower estimated medical costs over all three periods compared with patients in the primary care provider group.
Towards a Better Assessment of Pain and Suffering Damages for Personal Injuries: A Proposal Based on Quality Adjusted Life Years
In health care economics we are used to the concept of the cost of QALYs (quality adjusted life years
) by which the benefit of intervention, and then the benefit/cost ratio can be assessed.
Endoscopic ablation with photodynamic therapy cost more than endoscopic surveillance, esophagectomy, or no preventative strategy, but it provided the most discounted quality adjusted life years
(dQALYs) in a cost-effectiveness model.