pyruvate carboxylase
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Related to pyruvate carboxylase: gluconeogenesis
py·ru·vate car·box·yl·ase
ligase catalyzing reaction of ATP, pyruvate, and HCO32-, to form ADP, orthophosphate, and oxaloacetate; biotin and acetyl-CoA are involved; an absence of this enzyme results in neuronal loss in the cerebral cortex, leading to mental retardation.
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