Protective effects of pyrrolidine
dithiocarbamate on myocardium apoptosis induced by adriamycin in rats.
TLR4 inhibitor CLI-095 and NF-?B inhibitor pyrrolidine
dithiocarbamate (PDTC) were purchased separately from InvivoGen, Inc.
The polymer performs like a support for iron nitrate by means of steric/electrostatic stabilization with pyrrolidine
rings (amide functions) and methyl groups.
Based on this rationale, a N-substituted pyrrolidine
framework was used which incorporated a stereogenic alcohol functional group handle at the same relative position of the [sp.sup.3] ester oxygen in 3 (Scheme 1).
2 reduced stomach ulceration area from 12.62 [mm.sup.2] to 4.66 [mm.sup.2] (2.7 times decreasing), lysine derivative 3 reduced stomach ulceration area from 12.25 [mm.sup.2] to 3.13 [mm.sup.2] (3.9 times decreasing), and proline derivative 4 reduced stomach ulceration area from 12.62 [mm.sup.2] to 1.77 [mm.sup.2] (7.1 times decreasing).
Viscosity-temperature relationships of pyrrole and pyrrolidine
," Transactions of the Faraday Society, vol.
(3mL, 36 mmol) was added to a portion of the residual colorless liquid (1.5 g, 4.2 mmol), and the reaction mixture was refluxed with stirring overnight.
Like methanofullerenes, fulleropyrrolidines are efficient acceptors for OPV devices and, recently, it was established that the introduction of a thiophene moiety on the pyrrolidine
ring has a favorable effect on the power conversion energy (PCE) of a solar cell .
Zeng et al., "Blockade of NF-[kappa]B by pyrrolidine
dithiocarbamate attenuates myocardial inflammatory response and ventricular dysfunction following coronary microembolization induced by homologous microthrombi in rats," Basic Research in Cardiology, vol.
dithiocarbamate reduces lung injury caused by mesenteric ischemia/reperfusion in a rat model.
In previous study, we have found that the phase transition behavior of PNIPAAm-based polymer having pyrrolidine
groups as side chains was influenced by pH values .