pyrogenic threshold

pyrogenic threshold

An obsolete “unit”, defined as the number of malarial parasites required in the circulation to induce a paroxysm of fever.
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Historical RPT data shows injections of 0.5 EU/ml and 1 EU/ml demonstrated a febrile response (fail) in the rabbit model while injections less than 0.5 EU/ml did not exceed the pyrogenic threshold (pass).