analogue(redirected from pyrimidine analogue)
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1. a part or organ having the same function as another, but of different evolutionary origin.
2. a chemical compound having a structure similar to that of another but differing from it in respect to a certain component; it may have similar or opposite action metabolically. Also spelled analog.
nucleoside analogue a structural analogue of a nucleoside, a category that includes both purine analogues and pyrimidine analogues.
purine analogue a structural analogue of one of the purine bases(purine, adenine, or guanine); mercaptopurine and thioguanine are used as antineoplastics and azathioprine is an immunosuppressive. The antiviral agent vidarabine is an analogue of the adenine nucleoside adenosine.
pyrimidine analogue a structural analogue of one of the pyrimidine bases(cytosine, thymine, or uracil); fluorouracil and cytarabine are important antineoplastic agents.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
1. A compound that resembles another in structure but is not necessarily an isomer (for example, 5-fluorouracil is an analogue of thymine); analogues are often used to block enzymatic reactions by combining them with enzymes (for example, isopropyl thiogalactoside vs. lactose).
2. One of two organs or parts in different species of animals or plants that differ in structure or development but are similar in function.
[G. analogos, proportionate]
Farlex Partner Medical Dictionary © Farlex 2012
n. & adj.
Variant of analog.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
noun A compound that is structurally similar to another.
adjective An MRI term referring to or having a continuous range of values.
adjective Referring to data in the form of continuously variable (non-discrete) physical quantities, the mode in which most lab instruments produce information, where data is generated as non-discrete signals, as in AC or DC current, voltage changes or pulse amplitudes.
adjective Referring to a molecule that is structurally and functionally related to another molecule.
noun A molecule that is structurally and functionally related to another molecule.
noun A therapeutic agent with structural or chemical similarity to, or which mimics the effects of, another agent, but which differs chemically.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
an·a·logue, analog (an'ă-lawg)
1. One of two organs or parts in different species of animals or plants that differ in structure or development but are similar in function.
2. A compound that resembles another in structure but is not necessarily an isomer; analogues are often used to block enzymatic reactions by combining with enzymes.
[G. analogos, proportionate]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
A drug that is similar to the drug from which it is derived.
Mentioned in: Pituitary Tumors
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.