pyrimidine


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pyrimidine

 [pĭ-rim´ĭ-dēn]
an organic compound that is the fundamental form of the pyrimidine bases, which include cytosine, thymine, and uracil.

py·rim·i·dine (Pyr),

(pī-rim'i-dēn),
1,3-Diazine; a heterocyclic substance, the formal parent of several "bases" present in nucleic acids (uracil, thymine, cytosine) as well as of the barbiturates.

pyrimidine

(pī-rĭm′ĭ-dēn′, pĭ-)
n.
1. A single-ringed, crystalline organic base, C4H4N2, that is the parent compound of a large group of biologically important compounds.
2. Any of a group of substituted derivatives of pyrimidine, including the nitrogen bases uracil, cytosine, and thymine, which are components of nucleic acids. Barbiturates and certain other drugs are also pyrimidines.

py·rim·i·dine

(pir-im'i-dēn)
A heterocyclic substance, the formal parent of several "bases" present in nucleic acids (uracil, thymine, cytosine) as well as of the barbiturates.

pyrimidine

A nitrogenous base compound. Two pyrimidines, cytosine and thymine, are the DNA bases which, with two PURINES, form the genetic code. A third pyrimidine, uracil, takes the place of thymine in RNA.

pyrimidine

one of three types of bases found in NUCLEIC ACIDS, with a single ring structure. DNA contains CYTOSINE and THYMINE, RNA contains cytosine and URACIL. Pyrimidines always pair with PURINES in DNA.
References in periodicals archive ?
The 13C-NMR signals were found to be at 191.97 (benzoyl, C=O), 164.10 (pyrimidine, C=O), 160.38-114.08 (aromatic C), 56.09-55.65 (2CH3O-), 11.73 ppm (CH3-).
Such correlations (Figure 2) correspond to the protons of the phenyl group in position 2 of the pyrimidine ring.
However, the synthesis of chromophore c was performed using Chromophore a and 2-amino pyrimidine through a diazo coupling reaction with a prime aim to improve the high optical transparency, good thermal stability and good planarity.
(10) reported 62% of mucosal toxicity, similar to the 51.2% found in our series with use of pyrimidine antagonists.
Pathway enrichment and topology analysis identified enrichment in purine, pyrimidine, inositol phosphate, and branched-chain amino acid metabolism in addition to lysine degradation in both BMM and MDM.
Decitabine is a pyrimidine analogue of the nucleoside cytidine [1].
Pyrimidine derivatives Uracil and Thymine are an integral part of RNA and DNA, respectively.
UVB light passing through keratinocytes can cause DNA damage by inducing adjacent pyrimidine bases to form pyrimidine dimers [7].
Specifically, nucleic acids or their constituent purine or pyrimidine bases act as internal microbial markers of microbial protein synthesis [2].
Nucleosides including purine and pyrimidine nucleosides are reported to possess many interesting forms of biological and pharmacological activity, such as anti-infective activity [8], antiviral activity [9], anticancer activity [10], antioxidation activity [11], and immunological stimulation [12], which implies a need for large-scale production of nucleosides.