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A breakdown product of bone collagen, excreted in urine, and assayed as a measure of osteoclast activity; increased in disease states such as Paget disease, primary hyperparathyroidism, and postmenopausal osteoporosis.


A breakdown product of bone collagen, excreted in urine, and assayed as a measure of osteoclast activity; increased in disease states (e.g., Paget disease, primary hyperparathyroidism, osteoporosis).
References in periodicals archive ?
Jahan, Protonation of Higher Reduction Products of Pyridinium Salts, J.
Paraquat (PQ) (1,1-dimethyl-4, 4- bipyridinium dichloride), is a foliar-applied and non-selective bi- pyridinium herbicide, and one of the most widely used in controlling weeds in a huge variety of crops.
Similar to fluoroquinolones which were demonstrated earlier (30), it seems that hydroxylated surface of ZnO nanoparticles can interact with positively charged pyridinium ring nitrogen at position 3 and make a network between two molecules.
Relationship between urinary pyridinium cross-links, disease activity and disease subsets of ankylosing spondylitis.
Meloxicam protects cell damage from 1-methyl-4-phenyl pyridinium toxicity via the phosphatidylinositol 3-kinase/Akt pathway in human dopaminergic neuroblastoma SH-SY5Y cells," Brain Research, vol.
83] reported the use of the oxidative conversion of dihydropyridine to pyridinium ion and the metabolic trapping principle as an approach for measuring in vivo cerebral redox states.
When pH is increased, a collapsed conformation forms due to deprotonation of the charged pyridinium segments.
Coffee also contains pyridinium, which helps prevent excessive blood clotting.
Urinary excretion of pyridinium crosslinks of collagen in patients with osteoporosis and the effects of bone fracture.
aminomethylbenzotriazoles [14], polystyrenesupported proline as recyclable catalyst in the reaction of arylaldehydes and methyl or ethyl vinyl ketone [15], salicylic N-tosylimine with methyl, ethyl and vinyl ketones [16], bisphenol-based bifunctional organocatalyst [17], pyridinium ionic liquidsaccelerated amine-catalyzed [18], chiral bifunctional phosphine amides as catalysts [19, 20], ethyl acetate with methyl and ethyl vinyl ketone [21, 22].
Cationic head groups include imidazolium, pyridinium, pyrrolidinium, morpholinium, piperidium, quinolinium, quaternary ammonium, and quaternary phosphonium moieties; anionic head groups include tetrafluoroborate (B[F.
Assessment of the contributions of CYP3A4 and CYP3A5 in the metabolism of the antipsychotic agent haloperidol to its potentially neurotoxic pyridinium metabolite and effect of antidepressants on the bioactivation pathway.