pyrazolones

pyrazolones

A group of non-steroidal anti-inflammatory drugs that includes PHENYLBUTAZONE and azapropazone.
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9% convincingly reacted to a single drug (aspirin, pyrazolones, or diclofenac).
The hypersensitivity reaction most commonly occurred after paracetamol or pyrazolones.
This is particularly dangerous for diclofenac and pyrazolones, which are typical representatives of drugs that induce SNIUAA and should therefore be discouraged from re-administration unless a negative OPT with the culprit drug is reported (17, 26-29).
Moreover, the DPPH activity of dihydroxy pyrazolones is found higher than monohydroxy derivaitives.
Heterocyclic compounds have great pharmacological and medicinal influences, the pyrazolone class is one of them.
Figure 6 displays the powder diffraction patterns for the benzimidazolones PY151, PY154, and PO36, while the pyrazolones PO13 and PR41 are shown in Fig.
The five most intense lines for pyrazolone pigments are listed in Table 7.
4-acyl pyrazolones (Jensen 1959, Zolotov et al 1966, 1968, Karalova and Pyzhova 1968, Monseev and Monokhov 1968) have been shown to be good extraction reagents for metals in acidic solutions.
These include tricyclic antidepressants, neuroleptics, beta-blockers and other antiarrhythmics (CYP2D6); paracetamol, chlorzoxazone and ethanol (CYP2E1) and hydrazines, arylamines, pyrazolones, caffeine and nitrazepam (NAT2) among others.
Pyrazolones have also been employed in the synthesis of other heterocycles [12], in the separation of lanthanides , dyes preparation [13].
On TLC two products were observed, which were separated by silica gel column chromatography , identified as mono- , disubstituted pyrazolones.