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A class of nonsteroidal anti-inflammatory agents used in the treatment of arthritic conditions; for example, phenylbutazone.
Farlex Partner Medical Dictionary © Farlex 2012


A class of nonsteroidal anti-inflammatory agents used to treat arthritic conditions.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Physicochemical studies of symmetrical tetradentate schiff base complexes of chromium(III), cobalt(II), nickel(II), copper(II), zinc(II), oxovanadium(IV) and dioxouranium(VI) derived from 4-acyl pyrazolone and 1,4-diamine.
More recently, other pyrazolone derivatives have been synthesized and have experimentally demonstrated effective analgesic, anti-inflammatory, antiplatelet, and anticonvulsant activities, among other effects (3).
Metamizole is a pyrazolone derivate with antipyretic and analgesic properties.
On the other hand, the wide range of biological activities of pyrazolone as antitumor [12], anti-inflammatory [13] and antimicrobial [14] makes it a basic objective to synthesize biologically active transition metal complexes as it is known that the formation of the complexes enhances the biological efficiency of the ligand [15].
Among the more commonly implicated are pyrazolone derivatives, carbamazepine, hydantoin derivatives, cimetidine, lithium salts and gold salts.
PHZ is a pyrazolone derivative with basic properties used as anti-inflammatory and stabilizer for DD aqueous preparation since the latter is only stable for 2-3 days [2, 3].
(3) Other common culprits include the antipyretic metamizole and other pyrazolone derivatives such as tetracycline, metronidazole, ciprofloxacin, and phenytoin sodium.
IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone.