A total of 5 captive wild carnivores (lion-1, leopards2, hyaena-1 and jackal-1) suffering from moderate to heavy helminthic infection (EPG ranging from 600-1800) were treated with Prazisam plus (a) tablets (each tablet having Fenbendazole-500mg,
Pyrantel pamoate-144mg and Praziquantel-50mg) @ 1tab/ 10 kg.
Baits were similar to oral rabies vaccine baits and consisted of a hollow fishmeal polymer food attractant (15 g, 33 mm x 32 mm x 21 mm) in which we placed 180 mg (base) of
pyrantel pamoate mixed with marshmallow creme, which was sealed within the hollow chamber with paraffin wax.
As just a few examples, milbemycin oxime and moxidectin are included in a number of heartworm preventive drugs, and are also credited with effectiveness against roundworms, hookworms, and whipworms;
pyrantel pamoate (the "plus" in Heartgard Plus) is effective against roundworms and hookworms only.
A single dose of
pyrantel pamoate at a dose of 10 mg/kg body weight was administered to subjects with helminth ova in a diarrhoeal stool sample (mebendazole is contraindicated in children aged under 2 years).
Hadju V, Stephenson LS, Abadi K, Mohammed HO, Bowman DD and RS Parker Improvements in appetite and growth in helminth-infected schoolboys three and seven weeks after a single dose of
pyrantel pamoate.
Parasites were treated in children over two years of age via 100 mg of mebendazol; using
pyrantel pamoate in children under two years of age.
Patients with pinworm infection are initially treated with 1 dose of oral mebendazole (100 mg), albendazole (400 mg), or
pyrantel pamoate (11 mg/kg, maximum dose 1 g) (strength of recommendation [SOR] B).
3 ml recommended for neonates (0 - 6 months), 5 ml prescribed 5 ml/d recommended for children, 15 ml/d prescribed Folic acid 2 - 5 mg per day recommended for children 1 - 5 years, 15 mg/d prescribed
Pyrantel pamoate 2 tablets or 5 ml suspension recommended for children 2 - 6 years, 10 ml single dose prescribed for 2-year-old child Vitamin C 100 - 200 mg/24 h recommended, 300 mg/24 h frequently prescribed Promethazine 5 - 15 mg recommended for children 2 - 5 years, 37.
The fact that tribendimidine is different from albendazole, but has the same level of effectiveness, and is in the same class as
pyrantel and levamisole should increase people's comfort level in using this new drug," said Aroian.
A combination product of praziquantel,
pyrantel pamoate, and febantel has been shown to decrease cyst excretion in infected dogs.
The best method of deworming against tapeworms is to use a high dose of
pyrantel pamoate.
Urbani and Albonico (2003) while confirming four anthelminthic drugs namely: Albendazole, Levamisole, Mebendazole and
Pyrantel as appropriate single dose treatment against soil-transmitted helminthiasis, sounded a note of caution on reported side effects and severe adverse reactions associated with the drugs.
