CAU: caudate nucleus; GPe: external globus pallidus; GPi: internal globus pallidus; L: left; PUT: putamen
; R: right.
In our case, the DaTSCAN revealed abnormal tracer uptake in the left caudate nucleus and reduced tracer uptake in the putamina (especially in the left putamen
); these findings were coherent with the patient's symptoms of right-sided bradykinesia.
Peak MNI (mm) Brain region x y z L cerebellum posterior lobe -33 -78 -51 L superior orbital lobe (rectal gyrus) -12 45 -27 R middle occipital gyrus 54 -69 -12 R putamen
27 6 0 L putamen
-21 9 3 R superior temporal gyrus 63 -27 15 L superior temporal gyrus -63 -30 9 Peak T value Number Brain region of voxels L cerebellum posterior lobe -8.1425 115 L superior orbital lobe (rectal gyrus) -8.6597 70 R middle occipital gyrus -7.4936 59 R putamen
-9.4527 262 L putamen
-7.3238 146 R superior temporal gyrus 7.5155 192 L superior temporal gyrus 7.0531 57 R: right; L: left; MNI: Montreal Neurological Institute.
The comparison between control and svPPA groups showed only connectivity differences between the right operculum and the left putamen
(Figure 1(b) and Table S2).
###No.###Ventricle Ventricle Ventricle Putamen
These significantly different nodes were mainly concentrated in the bilateral lenticular nucleus: the putamen
; bilateral lingual gyrus; bilateral amygdala; bilateral thalamus; bilateral median cingulate and paracingulate gyri; right posterior cingulate gyrus; bilateral cuneus; left anterior cingulate and paracingulate gyri; right superior frontal gyrus, orbital part; right middle frontal gyrus; right temporal pole; middle temporal gyrus; left precentral gyrus; right lenticular nucleus; pallidum; and so forth.
Distribution volume ratio (DVR) of [[sup.11]C]TMSX ([7-N-methyl-[sup.11]C]-(E)-8-(3,4,5-trimethoxystyryl)-1,3,7-trimethylxanthine) binding in the putamen
was shown to be higher in PD patients with dyskinesias (disease duration: 11.1 [+ or -] 7.2 years) compared to healthy controls .
The patients were dosed with 20 million CTX cells which were injected by way of a routine surgical procedure into the putamen
, the region of the brain involved in learning and coordinating movement.
One important point is that in the majority of the cases the insular arteries primarily supply the insular cortex, extreme capsule, and, occasionally, the claustrum and external capsule, but not the putamen
, globus pallidus, or internal capsule, which are vascularized by the lateral lenticulostriate arteries (LLAs), although some thicker branches from M2 may anastomose with the LAAs.
The focus of this work is to develop a system, which can assist doctors and bio-informatics practitioners in the diagnosis of PD in the early stages itself by monitoring the changes in the putamen
and caudate regions of the brain and by measuring the eye-hand coordination level.
However, in 2008 scientists analysed MRI images of the human brain and discovered the same part - the putamen
- lights up whenever we feel love or hate.
Signal changes in the putamen
and globus pallidus were observed bilaterally and unilaterally in the MRI of cases 1 and 3, respectively Detailed examination did not reveal any clinical findings regarding the extrapyramidal system involvement, although it has been occasionally reported in the literature (6,13,17,18,19).