microphthalmos

(redirected from pure. microphthalmos)

microphthalmos

 [mi″krof-thal´mus]
a developmental defect causing moderate or severe reduction in size of the eye.

mi·croph·thal·mos

(mī'krof-thal'mos),
Abnormal smallness of the eye.
[micro + G. ophthalmos, eye]

microphthalmos

/mi·croph·thal·mos/ (mi″krof-thal´mus) abnormal smallness in all dimensions of one or both eyes.

microphthalmos

[mī′krəfthal′məs]
Etymology: Gk, mikros + ophthalmos, eye
a developmental anomaly characterized by abnormal smallness of one or both eyes. When the condition occurs in the absence of other ocular defects, it is called pure microphthalmos or nanophthalmos. Also spelled microphthalmus. Also called microphthalmia. microphthalmic, adj.
enlarge picture
Left microphthalmos and bilateral iris colobomas

microphthalmia

A congenital reduction in eye size, with the ocular bulb measuring 1/2 of the normal volume in extreme cases, due to an abnormal development of the optic vesicle in the optic cup.

Aetiology
• Congenital—e.g., encephalo-ophthalmic dysplasia, focal dermal hypoplasia, Hallermann-Streiff syndrome, incontinentia pigmenti, Lenz microphthalmia syndrome, retinopathy of prematurity, trisomy 13-15.
• Infectious—e.g., CMV, herpes, rubella, toxoplasmosis.
• Toxins—e.g., foetal alcohol syndrome.

Incidence
14/105; 3–11% of all cases of blindness.

mi·croph·thal·mos

(mī'krof-thal'mŏs)
Abnormal smallness of the eye.
[micro- + G. ophthalmos, eye]

microphthalmos

The state of having an abnormally small eyeball. In severe degrees there is usually a gross defect of vision.

mi·croph·thal·mos

, microphthalmia (mī'krof-thal'mŏs, -mē-ă)
Abnormal smallness of the eye.
[micro- + G. ophthalmos, eye]

microphthalmos,

n a developmental anomaly characterized by abnormal smallness of one or both eyes.

microphthalmos

abnormal smallness in all dimensions of one or both eyes, sometimes in association with other ocular abnormalities. Recorded as occurring in piglets from sows on vitamin A-deficient diets in early pregnancy, and in dogs, where it is associated with collie eye anomaly and is an inherited defect in some breeds.

pure. microphthalmos