pulmonary vascular resistance

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1. opposition, or counteracting force, as opposition of a conductor to passage of electricity or other energy or substance.
2. the natural ability of a normal organism to remain unaffected by noxious agents in its environment; see also immunity.
3. in psychology or psychiatry, conscious or unconscious defenses against change, preventing repressed material from coming into awareness; they can take such forms as forgetfulness, evasions, embarrassment, mental blocks, denial, anger, superficial talk, intellectualization, or intensification of symptoms. It occurs because the blocked association or understanding would be too threatening to face at this point in the therapy; identification of what point the resistance comes at can be an important indicator of the patient's unconscious patterns.
airway resistance the opposition of the tissues of the air passages to air flow: the mouth-to-alveoli pressure difference divided by the rate of air flow. Symbol RA or RAW.
androgen resistance resistance of target organs to the action of androgens, resulting in any of a spectrum of defects from a normal male phenotype in which men have normal genitalia but infertility to complete androgen resistance in which the individual has a female phenotype. Complete androgen resistance is an extreme form of male pseudohermaphroditism in which the individual is phenotypically female but is of XY chromosomal sex; there may be rudimentary uterus and tubes, but the gonads are typically testes, which may be abdominal or inguinal in position. Called also testicular feminization and testicular feminization syndrome. Incomplete androgen resistance is any of various forms less than the complete type, manifested by a male phenotype with various degrees of ambiguous genitalia such as hypospadias and a small vaginal pouch, a hooded phallus, or a bifid scrotum that may or may not contain gonads.
drug resistance the ability of a microorganism to withstand the effects of a drug that are lethal to most members of its species.
insulin resistance see insulin resistance.
multidrug resistance (multiple drug resistance) a phenomenon seen in some malignant cell lines: cells that have developed natural resistance to a single cytotoxic compound are also resistant to structurally unrelated chemotherapy agents. Called also cross-resistance.
peripheral resistance resistance to the passage of blood through the small blood vessels, especially the arterioles.
pulmonary vascular resistance the vascular resistance of the pulmonary circulation; the difference between the mean pulmonary arterial pressure and the left atrial filling pressure divided by the cardiac output. Called also total pulmonary vascular resistance.
total peripheral resistance the vascular resistance of the systemic circulation: the difference between the mean arterial pressure and central venous pressure divided by the cardiac output.
total pulmonary resistance (total pulmonary vascular resistance) pulmonary vascular resistance.
vascular resistance the opposition to blood flow in a vascular bed; the pressure drop across the bed divided by the blood flow, conventionally expressed in peripheral resistance units. Symbol R or R.

pulmonary vascular resistance (PVR)

the resistance in the pulmonary vascular bed against which the right ventricle must eject blood.

pul·mo·nar·y vas·cu·lar re·sis·tance

(pul'mŏ-nar-ē vas'kyū-lăr rĕ-zistăns)
The resistance to blood flow through the pulmonary circulation, which is largely influenced by the degree of tone or caliber of the pulmonary arteries and capillaries. Can be measured with the use of hemodynamic monitoring.
References in periodicals archive ?
Pulmonary vascular responses to nitrous oxide in patients with normal and high pulmonary vascular resistance.
Right ventricular abnormalities in sickle cell anemia: evidence of a progressive increase in pulmonary vascular resistance.
6 Anaesthesia related risk factors for perioperative pulmonary hypertensive crisis are hypercarbia, hypoxia, painful stimuli, acidosis and airway instrumentation, which leads to rapid increase in pulmonary vascular resistance.
Epoprostenol caused a long-term reduction in pulmonary vascular resistance exceeding that which could be achieved through vasodilator challenge, which is consistent with the drug's progressive effect on the pulmonary vasculature when administered over time.
PAH can lead to restrictions in pulmonary blood flow, and characteristic progressive elevations in pulmonary vascular resistance.
Nitrous oxide was avoided as it is known to increase pulmonary vascular resistance and heart rate.
The principal goal during the induction of anesthesia will be maintaining a balance between the pulmonary vascular resistance (PVR) and the systemic vascular resistance (SVR).
5] The critical factor determining prognosis in all the patients undergoing surgery is the degree to which the pulmonary vascular resistance is elevated before the surgery.
While the guidelines recommend against targeted therapies for RHC-confirmed PH, a trial of either a prostanoid or an endothelin-receptor antagonist is recommended for patients with confirmed PH and elevated pulmonary vascular resistance, normal pulmonary capillary wedge pressure, and related symptoms.
Following at suitable interval when the pulmonary artery hypertension and the pulmonary vascular resistance were overcome the definitive repair of VSD(s) was carried out by putting a synthetic patch at the defect.
Cardiac catheterization is rarely indicated and reserved for patients who present after early infancy and, therefore, are at risk for elevated pulmonary vascular resistance, or any patient in whom the anatomy cannot be adequately defined by echocardiography.
Prostaglandin inhibition prevents the fall in pulmonary vascular resistance as a result of rhythmic distension of the lungs in fetal lambs.

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