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Term loosely used for any of the compounds containing pteridine; specifically, 2-amino-4-hydroxypteridine. Some pteridines (for example, xanthopterin, leucopterin) still retain the pterin root.
References in periodicals archive ?
He had normal urinary pterins and dihydropteridine reductase activity.
Natural folates are all, to varying degrees, unstable, particularly to oxidative cleavage between the pterin and pABA moieties (Fig.
The first step of the plant pterin branch is catalyzed by an unusual GTP cyclohydrolase I (GTPCHI, Fig.
Our studies focus on the exact role BH4 using pterin analogs that are substituted at positions that directly hydrogen bond to the heme in the active site.
These conditions can be detected only by abnormal monoamine metabolite and pterin profiles in CSF (57).
This disappearance is due to the instability of serum folate species, which undergo oxidative cleavage of the C9-N10 bond and oxidation of the pterin ring (24).
4] deficiencies is based on neonatal screening for phenylketonuria and urinary pterin analysis (17).
Pterin concentrations in the urine were within the reference interval.
Prenatal diagnosis of PTPS deficiency at 15-24 weeks gestation has been made on the basis of pterin concentrations in amniotic fluid and enzymatic activity in fetal erythrocytes (7).
This latter pterin derivative has long been known to be an essential cofactor for the enzymes involved in hydroxylation of aromatic amino acids (i.
However, 6-FP, like many other pterins, is known to be a potent inhibitor of xanthine oxidase [22].